DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2256 and Rcvrn

DIOPT Version :9

Sequence 1:	NP_572437.2	Gene:	CG2256 / 31727	FlyBaseID:	FBgn0029995	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_033064.1	Gene:	Rcvrn / 19674	MGIID:	97883	Length:	202	Species:	Mus musculus

Alignment Length:	204	Identity:	46/204 - (22%)
Similarity:	91/204 - (44%)	Gaps:	33/204 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 SGKVNPKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVEGIDR 169
            ||.::.::|:.|:..|:||::||.|.   |:..:..|....                     |.|
Mouse     6 SGALSKEILEELQLNTKFTEEELSAW---YQSFLKECPSGR---------------------ITR 46

  Fly   170 IVFRELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPAERAAFCFRVYD 234
            ..|..:....|.....:...:.:|.|:|...:| .|..:.::|.|.....|.|.::..:.|.:||
Mouse    47 QEFESIYSKFFPDSDPKAYAQHVFRSFDANSDG-TLDFKEYVIALHMTTAGKPTQKLEWAFSLYD 110

  Fly   235 LNTDGFITKDEMFTLLRNCLIKQPQDED----PDE--GVKDLVEIVLKKFDLDKDGKVSLEDFM- 292
            ::.:|.|:|:|:..::. .:.|..:.||    ||:  ..:...|.:...|...:|.|::.|:|:
Mouse   111 VDGNGTISKNEVLEIVM-AIFKMIKPEDVKLLPDDENTPEKRAEKIWAFFGKKEDDKLTEEEFIE 174

  Fly   293 GTVTAEPLL 301
            ||:..:.:|
Mouse   175 GTLANKEIL 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	17/69 (25%)
CG2256	NP_572437.2	EF-hand_7	229..292	CDD:290234	17/68 (25%)
Rcvrn	NP_033064.1	FRQ1	14..182	CDD:227455	43/193 (22%)
		EFh	<37..90	CDD:298682	11/74 (15%)
		EFh	65..127	CDD:238008	16/62 (26%)
		EFh	101..175	CDD:238008	18/74 (24%)
		Interaction with GRK1. /evidence=ECO:0000250\|UniProtKB:P21457	189..192
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900