DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2256 and guca1a

DIOPT Version :9

Sequence 1:	NP_572437.2	Gene:	CG2256 / 31727	FlyBaseID:	FBgn0029995	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_571945.1	Gene:	guca1a / 140430	ZFINID:	ZDB-GENE-011128-5	Length:	189	Species:	Danio rerio

Alignment Length:	192	Identity:	38/192 - (19%)
Similarity:	84/192 - (43%)	Gaps:	25/192 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 TRFTKDELDA--LCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVEGIDRIVFRELLHSTFDI 182
            |..|.|:|.|  :...|:|.::.|.....||..       .|....:.|:|
Zfish     5 TGSTVDDLQAVEMHLWYKKFMTECPSGQLTLHE-------FKQFFGLRGLD-------------- 48

  Fly   183 VTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPAERAAFCFRVYDLNTDGFITKDEMF 247
            ......:|::|.::|...:|....:| ::..||..:||....:..:.|::||::.:|.|.:.|:.
Zfish    49 PKANAYIEQMFRTFDMNKDGYIDFME-YVAALSLVMRGKMEHKLRWYFKLYDVDGNGCIDRYELL 112

  Fly   248 TLLRNCLIKQPQDEDPDEGVKDLVEIVLKKFDLDKDGKVSLEDFMGTVTAEPLLIEAFGQCL 309
            .::: .:......|..:...::....|.::.|::.||::||::|:....::...:|...:.|
Zfish   113 NIIK-AIRAINGSETQESSAEEFTNRVFERIDINGDGELSLDEFVAGARSDEEFMEVMMKSL 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	13/63 (21%)
CG2256	NP_572437.2	EF-hand_7	229..292	CDD:290234	13/62 (21%)
guca1a	NP_571945.1	EFh	<27..76	CDD:298682	11/70 (16%)
		EFh	54..116	CDD:238008	15/62 (24%)
		EF-hand_7	55..115	CDD:290234	15/60 (25%)
		EFh	90..160	CDD:238008	14/70 (20%)
		EF-hand_7	91..157	CDD:290234	14/66 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810