Protein Alignment Ldsdh1 and DHRS3

DIOPT Version :9

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_004744.2
• Gene: DHRS3 / 9249
• HGNCID: 17693
• Length: 302
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 88/293 - (30%)
• Similarity: 152/293 - (51%)
• Gaps: 11/293 - (3%)

  Fly    22 IVLLVVDIVMLIVKFWLAIAEAIVGLFRAPPLDDVNGKVVLITGTGHGMGKEMALQYAKLGA-TI 85
            :|:..:.::.|:||       |.|||.....|.|::.:.|||||.|.|:|:::|.::|:.|| .|
Human     9 LVMFPLQMIYLVVK-------AAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKI 66

  Fly    86 LCWDVNEQTNNQTVKEIKNNGGKAFGYVCNVTKREELIELAQKVRKEHGFIHVVVNNAGIMPCHP 150
            :.|...|:...:|.:||:..|.:...::|:|..|||:.:.|:.||::.|.|.::||||.::....
Human    67 VLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKS 131

  Fly   151 LLEHTENEIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVR 215
            |::..::.:.....||.|..||..:||||.|:|...|.||.|:|...|..:...:.||.:|.:..
Human   132 LMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAF 196

  Fly   216 GYMAALVEELRQKNPQNNVKLTTIYPYMIDTGLCKNPRYRFPNLFKLIPADVAAGSIIEAQRQGL 280
            .:|.:|...|..   ...|..||:.|:...|.:.:..|.||||||..:..:..|...:||.:...
Human   197 AFMESLTLGLLD---CPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQ 258

  Fly   281 EEAAIPRHFVAAEKIGRLIPRKAMRLVNDFFDT 313
            ....:|....|...:..::|:.|:..::.|..|
Human   259 ALLLLPWTMHALVILKSILPQAALEEIHKFSGT 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	adh_short	59..248	CDD:278532	62/189 (33%)
		NADB_Rossmann	60..287	CDD:304358	72/227 (32%)
DHRS3	NP_004744.2	17beta-HSDXI-like_SDR_c	53..281	CDD:187598	67/230 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920