Protein Alignment Ldsdh1 and SRL4

DIOPT Version :10

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_015292.1
• Gene: SRL4 / 856074
• SGDID: S000005954
• Length: 281
• Species: Saccharomyces cerevisiae
• Alignment Length: 214
• Identity: 44/214 - (20%)
• Similarity: 78/214 - (36%)
• Gaps: 57/214 - (26%)

  Fly    53 LDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKNNGGKAFGYVCN-- 115
            ::|.:.||:.|.......||. |.:..||...|.|.|.::      :|.::    ::..|:.|
Yeast    48 IEDYHTKVINIDTIDSINGKN-ARRSEKLYTFISCKDFSD------IKCLE----ESMLYLQNLE 101

  Fly   116 ------VTKREELIELAQKVRKEHGFIHVVVNNAGIMPCHPLLEHTENEIRLMYEINVLSHFWII 174
                  :...:|.||  ..:.||..|:.             |.|.:.||...:...|:.|...|.
Yeast   102 IIPTVLINNMQEGIE--STLLKEDKFLR-------------LDEESLNEFEKIVRYNLQSVILIT 151

  Fly   175 QAFLPDMIER---------------NEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEE 224
            :..|.::..:               |..|::.|..|..  |...:...||    :..:...:..|
Yeast   152 KFCLSNIFPKVQAEAQEKAKGFYIVNISSVLTLKPCKS--GTHFITSKCG----INSFHDGITSE 210

  Fly   225 LRQKNPQNNVKLTTIYPYM 243
            |:.|:...|||  |:..|:
Yeast   211 LKLKDSNLNVK--TLIAYL 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	42/207 (20%)
SRL4	NP_015292.1	Rossmann-fold NAD(P)(+)-binding proteins	28..>230	CDD:473865	44/214 (21%)