Protein Alignment Ldsdh1 and TDA5

DIOPT Version :10

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_013530.1
• Gene: TDA5 / 851146
• SGDID: S000004418
• Length: 326
• Species: Saccharomyces cerevisiae
• Alignment Length: 305
• Identity: 70/305 - (22%)
• Similarity: 124/305 - (40%)
• Gaps: 38/305 - (12%)

  Fly    23 VLLVVDIVMLIVKFWLAIAEAIV---GLFRAPPLDDVNGKVVLITGTGHGMGKEMALQ----YAK 80
            :.:.:.|..|::..:| ||.:.:   |......|.:....:|||||...|:|:.:..|    |:.
Yeast    33 ISICLTIYTLLINAFL-IANSYIKRSGQVAWKSLREFKNGIVLITGGSKGLGRAIVSQLLQDYSN 96

  Fly    81 LGATILCWDV-NEQTNNQTVKEIKNNGGKAFGYVCNVTKREELIELAQKV-RKEHGFIHVVVNNA 143
            |  |||..|: .....|..||::          :|:::..||:..|...: ||....|.::||||
Yeast    97 L--TILNVDICPSSVRNTRVKDL----------ICDLSDDEEVAALLNLLKRKYKNEIRLIVNNA 149

  Fly   144 GIMPCHPLLEHTENE-IRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPY 207
            |:..........|.: :..:::||..:....||...|......:..||.::|..|:.....:..|
Yeast   150 GVRANFTGFNGMERDNLDKIFKINTFAPLQFIQELAPSRHSTRQCYIVNIASILGILTPAKVAAY 214

  Fly   208 CGTKFAVRGYMAALVEELRQKNPQNNVKLTTIYPYMIDTGL---CKNPRYRFPNLFKLIPADVAA 269
            ..:|.|:..:..:...|| |.....|::...:.|..::|.:   .|.||..|.   .:|.....|
Yeast   215 AASKAALIAFHQSYSFEL-QNEGVRNIRTLLVTPGQLNTEMFAGFKPPRQFFA---PVIDITTLA 275

  Fly   270 GSIIE----AQRQGLEEAAIPRHFVAAEKIGRLIPRKAMRLVNDF 310
            ..|:.    .||..|.|.    .:.:...:...:|....|:|..|
Yeast   276 AKIVRYCELGQRGQLNEP----FYCSFAHLLMCVPYSLQRIVRSF 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	59/240 (25%)
TDA5	NP_013530.1	Rossmann-fold NAD(P)(+)-binding proteins	72..309	CDD:473865	60/256 (23%)