Protein Alignment Ldsdh1 and BDH1

DIOPT Version :10

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: XP_011511369.1
• Gene: BDH1 / 622
• HGNCID: 1027
• Length: 347
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 57/205 - (27%)
• Similarity: 91/205 - (44%)
• Gaps: 17/205 - (8%)

  Fly    50 APPLDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKN-NGGKAFGYV 113
            |...:.|..|.||:||...|.|..:|......|..:....:.:...:..|||:.: |..:.....
Human    51 ASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQ 115

  Fly   114 CNVTKREELIELAQKVRK-----EHGFIHVVVNNAGIMPCHPLLEHTENE-IRLMYEINVLSHFW 172
            .||...||:.::.:.||.     |.| :..:||||||..... :|.|..| .:.:.|:|:.....
Human   116 LNVCSSEEVEKVVEIVRSSLKDPEKG-MWGLVNNAGISTFGE-VEFTSLETYKQVAEVNLWGTVR 178

  Fly   173 IIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGY-------MAALVEELRQKNP 230
            :.::||| :|.|.:|.:|.:||..|........|||.|||.|..:       |..|..::....|
Human   179 MTKSFLP-LIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEP 242

  Fly   231 QNNVKLTTIY 240
            .|.:..|::|
Human   243 GNFIAATSLY 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	54/195 (28%)
BDH1	XP_011511369.1	type2_17beta_HSD-like_SDR_c	60..345	CDD:187665	55/196 (28%)