Protein Alignment Ldsdh1 and hsd17b13

DIOPT Version :10

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001011240.1
• Gene: hsd17b13 / 496682
• XenbaseID: XB-GENE-995635
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 235
• Identity: 76/235 - (32%)
• Similarity: 142/235 - (60%)
• Gaps: 4/235 - (1%)

  Fly    21 NIVLLVVDIVMLIVKFWLAIAEAIVGLFRAPPLDDVNGKVVLITGTGHGMGKEMALQYAKLGATI 85
            ||:|..:.::.:.|..::   |:.|.||.......|.|.:|||||:|||:|:..||::||..:.:
 Frog     2 NIILEYMFLLFIAVYSYM---ESFVKLFLPVNRKSVAGNIVLITGSGHGIGRRTALEFAKHESIL 63

  Fly    86 LCWDVNEQTNNQTVKEIKNNGGKAFGYVCNVTKREELIELAQKVRKEHGFIHVVVNNAGIMPCHP 150
            :.||:|::...:|..|.:..|..|:.:|.:.:.|.::...|:||:::.|.:.:::||||::....
 Frog    64 VLWDINQKGVEETADECRKLGATAYAFVVDCSTRNDIYRCAEKVKQDIGDVDILINNAGVVFGTE 128

  Fly   151 LLEHTENEIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVR 215
            .|:..:::|...:.:|:|:|||..::||..|::::.|.||.::|.||..|:..||.||.:||.:.
 Frog   129 FLKLQDHQIEKTFSVNILAHFWTTKSFLSAMMKKDRGHIVTVASIAGQLGVPYLVDYCASKFGLV 193

  Fly   216 GYMAALVEELRQKNPQNNVKLTTIYPYMIDTGLCKNPRYR 255
            |:..:|..||:... ::.||.|.:.|..::||..:||..|
 Frog   194 GFHESLTSELKLLG-KDGVKTTCLCPVFVNTGFVQNPSTR 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	66/196 (34%)
hsd17b13	NP_001011240.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	66/196 (34%)