Protein Alignment Ldsdh1 and hsd20b2

DIOPT Version :10

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001373557.1
• Gene: hsd20b2 / 368367
• ZFINID: ZDB-GENE-030804-21
• Length: 329
• Species: Danio rerio
• Alignment Length: 258
• Identity: 59/258 - (22%)
• Similarity: 107/258 - (41%)
• Gaps: 45/258 - (17%)

  Fly    20 YNIVLLVVDIVMLIV-------KFWLAIAEAIVG-LFRAPPLDDVN--GKVVLITGTGHGMGKEM 74
            |:|||..:..|.::.       :.|......::. ::|.    |:.  |:..::||...|:|:..
Zfish    10 YSIVLCGIGCVTVVYYMLRWSWQCWHGFKVYVISEIWRT----DLRTYGRWAVVTGATSGIGRAY 70

  Fly    75 ALQYAKLGATILCWDVNEQTNNQTVKEIKNNGG-----------KAFGYVCNVTKREELIELAQK 128
            |.:.||.|..|:....:|:..::..|||::...           :.......:||:.|.:|
Zfish    71 AEELAKRGLNIVLISRSEEKLHRVAKEIEDKYNQKTHVIQADFTEGHSIYSTITKQLEGLE---- 131

  Fly   129 VRKEHGFIHVVVNNAGIMPCHPL-----LEHTENEIRLMYEINVLSHFWIIQAFLPDMIERNEGS 188
                   |.::|||.|:.....|     :...:..|..:...|.||...:.:..||.|:||.:|.
Zfish   132 -------IGILVNNVGMNYIGVLANFLDVPDPDQRITQVLNCNTLSVTQMCRVILPGMVERGKGL 189

  Fly   189 IVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEELRQKNPQNNVKLTTIYPYMIDTGLCKN 251
            |:.:||.||...:..:..|..||..|..:...|..|.|.|    .:.:..:.|:|:.|.:..|
Zfish   190 IINISSEAGYQPVPMVSLYSATKAFVTYFSLGLNAEYRSK----GITVQCVAPFMVSTNMTHN 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	50/208 (24%)
hsd20b2	NP_001373557.1	17beta-HSD1_like_SDR_c	54..296	CDD:187614	51/210 (24%)