DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ldsdh1 and CG9265

DIOPT Version :9

Sequence 1:	NP_572436.1	Gene:	Ldsdh1 / 31726	FlyBaseID:	FBgn0029994	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001260655.1	Gene:	CG9265 / 35369	FlyBaseID:	FBgn0032910	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	237	Identity:	87/237 - (36%)
Similarity:	140/237 - (59%)	Gaps:	7/237 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PLDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKNNGGKAFGYVCNV 116
            |..::|..:.||||.|:|:|:.:|.:..|:|..::.||:|::...:||:.::..||...|||.::
  Fly    80 PEKELNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEEAGGYCKGYVVDI 144

  Fly   117 TKREELIELAQKVRKEHGFIHVVVNNAGIMPCHPLLEHTENEIRLMYEINVLSHFWIIQAFLPDM 181
            :|:||:.:.|..:|.|.|.|.:::||||::....||:..::.|...:.:||::|||..:||||.|
  Fly   145 SKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTPDHLIERSFNVNVMAHFWTTKAFLPKM 209

  Fly   182 IERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEELRQKNPQNNVKLTTIYPYMID- 245
            ||.:.|.|..::|.||..|:..||.||.:|||..|:..||..||.... ..|::.|.|.|:.|.
  Fly   210 IENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLG-HTNIRTTCICPFFIQA 273

  Fly   246 TGLCKNPRYRF-PNLFKLIPADVAAGSIIEAQRQGLEEAAIP 286
            ||:..:...|: |.   |.|.|| |..:|.|.|:..:.|.||
  Fly   274 TGMFDDVNARWVPT---LNPNDV-ADRVIAAIRKNEKLAVIP 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	adh_short	59..248	CDD:278532	71/189 (38%)
Ldsdh1	NP_572436.1	NADB_Rossmann	60..287	CDD:304358	85/229 (37%)
CG9265	NP_001260655.1	fabG	82..299	CDD:235546	80/221 (36%)
CG9265	NP_001260655.1	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	85/229 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447610
Domainoid	1	1.000	91	1.000	Domainoid score	I1741
eggNOG	1	0.900	-	-		E2759_KOG1201
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	96	1.000	Inparanoid score	I1486
Isobase	1	0.950	-	1	Normalized mean entropy	S1933
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	1	1.000	-	-		mtm9177
orthoMCL	1	0.900	-	-		OOG6_100599
Panther	1	1.100	-	-	P	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.750