Protein Alignment Ldsdh1 and Sdr16c6

DIOPT Version :10

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001074179.1
• Gene: Sdr16c6 / 242286
• MGIID: 2685269
• Length: 316
• Species: Mus musculus
• Alignment Length: 298
• Identity: 101/298 - (33%)
• Similarity: 164/298 - (55%)
• Gaps: 14/298 - (4%)

  Fly    26 VVDIVMLIVKFWLAIAEAIVGLFRAPP--LDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCW 88
            |.|..:...||.....|::|  |:..|  ..||:|::|||||.|.|:|:.:|:.:|..|||::.|
Mouse     4 VADTAIFFGKFLYYFLESLV--FKVIPKRKKDVSGEIVLITGAGSGLGRLLAIHFASHGATLVLW 66

  Fly    89 DVNEQTNNQTVKEIKNNGG-KAFGYVCNVTKREELIELAQKVRKEHGFIHVVVNNAGIMPCHPLL 152
            |:|::.|.:|.:.:|..|. |.|.|.|:.:.|.|:..:|.:|::|.|.:.:::||||::.....|
Mouse    67 DINQEGNMETCRLVKQKGDVKVFAYKCDCSSRIEVYRVADQVKEEVGDVTILINNAGVVTGKSFL 131

  Fly   153 EHTENEIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGY 217
            ...::.:...:.:|.:||||..:||||.|::.|.|.:|.:||.|||.|:..|..|..:|||..|:
Mouse   132 NTPDHLVEKSFLVNAISHFWTCKAFLPAMVKANHGHLVCISSIAGLVGINGLSDYSSSKFAAFGF 196

  Fly   218 MAALVEELRQKNPQNNVKLTTIYPYMIDTGLCKNPRYRFPNLFKLIPADVAAGSIIEAQRQGLEE 282
            ..:|..||.. ..:..||.|.:.||.|.||:.:....::|.|..|:..:..|..|..|.   |||
Mouse   197 AESLFLELTM-IMKTKVKSTIVCPYFIKTGMFEGCTTKYPLLLPLLEQEYVAQKIFNAI---LEE 257

  Fly   283 AA---IPRHFVAAEKIGRLIPRKAMRLVNDFFDTGVDT 317
            ..   ||:....|..:.::|..|.|..:.::.  ||||
Mouse   258 QVYLIIPKFAYVALFLKQIISPKMMIALGEYL--GVDT 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	81/230 (35%)
Sdr16c6	NP_001074179.1	17beta-HSDXI-like_SDR_c	38..276	CDD:187598	83/241 (34%)