Protein Alignment Ldsdh1 and SDR16C5

DIOPT Version :9

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001304978.1
• Gene: SDR16C5 / 195814
• HGNCID: 30311
• Length: 318
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 88/291 - (30%)
• Similarity: 154/291 - (52%)
• Gaps: 26/291 - (8%)

  Fly    29 IVMLIVKFWLAIAEAIVGLFRAPPLDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQ 93
            :.:.:.|...::.||::......|..:|.|::|||||.|.|:|:.:|||:|:||:.::.||:|::
Human    11 LFIFLGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKE 75

  Fly    94 TNNQTVKEIKNNGG-KAFGYVCNVTKREELIELAQKVRKEHGFIHVVVNNAGIMPCHPLLEHTEN 157
            .|.:|.|..:..|. :...|.|:.:::|.:..:|.:|:||.|.:.:::|||||:.....|:..:.
Human    76 GNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDE 140

  Fly   158 EIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYM-AAL 221
            .:...:::|..:|.|..:||||.||..:.|.:|.:||.|||.|:..|..||.:|||..|:. :..
Human   141 LMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVF 205

  Fly   222 VEELRQKNPQNNVKLTTIYPYMIDTGLCKNPRYRFPNLFKLIPADVAAGSIIEAQRQGLEEAAIP 286
            ||...||  |..:|.|.:.|:.|.||:.:......|:|..::....|...|:||
Human   206 VETFVQK--QKGIKTTIVCPFFIKTGMFEGCTTGCPSLLPILEPKYAVEKIVEA----------- 257

  Fly   287 RHFVAAEKIGRLIPR--------KAMRLVND 309
               :..||:...:|:        |.:.|..|
Human   258 ---ILQEKMYLYMPKLLYFMMFLKRLHLAQD 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	adh_short	59..248	CDD:278532	69/190 (36%)
		NADB_Rossmann	60..287	CDD:304358	76/228 (33%)
SDR16C5	NP_001304978.1	adh_short	41..231	CDD:278532	70/191 (37%)
		17beta-HSDXI-like_SDR_c	42..280	CDD:187598	80/253 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100599
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.820