Protein Alignment Ldsdh1 and dhs-4

DIOPT Version :10

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_492563.1
• Gene: dhs-4 / 172810
• WormBaseID: WBGene00000968
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 295
• Identity: 97/295 - (32%)
• Similarity: 161/295 - (54%)
• Gaps: 12/295 - (4%)

  Fly    25 LVVDIVMLIVKFWLAIAEAIVGLFRAP------PLDDVNGKVVLITGTGHGMGKEMALQYAKLGA 83
            ::::||:|:...   :.:.::.|.:..      |..|:..|.|||||.|:|:||.:|.::|..||
 Worm     4 IILEIVILLFNL---LIQNLISLIKYALPYSLLPKKDLYRKKVLITGAGNGLGKLLAQKFAARGA 65

  Fly    84 TILCWDVNEQTNNQTVKEIKNNGGKAFGYVCNVTKREELIELAQKVRKEHGFIHVVVNNAGIMPC 148
            |::.||:|.|:.::...||:.|.|:|..|..|:....::.::.|:|..:.|.:.::||||||...
 Worm    66 TLILWDINLQSVDELKNEIRGNQGEAHSYEVNLCDPGKIAQVGQQVINDIGKVDILVNNAGIATA 130

  Fly   149 HPLLEHTENEIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFA 213
            ..:|:.:||||...:::||.:||:.:|.|||.|::.|.|.||.::|.||..|...|..|..||.|
 Worm   131 KMILDSSENEINRSFDVNVKAHFYTVQQFLPAMLKDNNGHIVTIASAAGKMGSSGLADYSSTKHA 195

  Fly   214 VRGYMAALVEELRQKNPQNNVKLTTIYPYMIDTGL--CKNPRYRFPNLFKLIPADVAAGSIIEAQ 276
            ..|:..:||.|: .::.:|.||.|.:.||.:.|.:  ......|||.:|.::..|.....|.||.
 Worm   196 AVGFHDSLVAEI-MESEKNGVKTTLVCPYYVHTSMFDATGAATRFPWIFPILDTDYVVQKIFEAI 259

  Fly   277 RQGLEEAAIPRHFVAAEKIGRLIPRKAMRLVNDFF 311
            ....|....||.|.......:::|.||..:|..||
 Worm   260 ETEQEFLVTPRAFYLVFAGIQILPYKAQAMVAQFF 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	81/228 (36%)
dhs-4	NP_492563.1	17beta-HSDXI-like_SDR_c	43..286	CDD:187598	85/243 (35%)