Protein Alignment Ldsdh1 and Hsd17b11

DIOPT Version :9

• Sequence 1: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_444492.1
• Gene: Hsd17b11 / 114664
• MGIID: 2149821
• Length: 298
• Species: Mus musculus
• Alignment Length: 298
• Identity: 92/298 - (30%)
• Similarity: 163/298 - (54%)
• Gaps: 16/298 - (5%)

  Fly    26 VVDIVMLIVKFWLAIAEAIVGLFRAPPLDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDV 90
            ::|:::|:....:...|::|.||.......|.|::|||||.|||:|:..|.::|||...::.||:
Mouse     4 LLDLILLLPLLIVFSIESLVKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDI 68

  Fly    91 NEQTNNQTVKEIKNNGGKAFGYVCNVTKREELIELAQKVRKEHGFIHVVVNNAGIMPCHPLLEHT 155
            |:....:|..:.:..|.:|..:|.:.::|||:...|:||::|.|.:.::|||||::....|....
Mouse    69 NKNGIEETAAKCRKLGAQAHPFVVDCSQREEIYSAAKKVKEEVGDVSILVNNAGVVYTADLFATQ 133

  Fly   156 ENEIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAA 220
            :.:|...:|:|||:|||..:||||.|::.|.|.||.::|.||...:..|:.||.:|||..|:..|
Mouse   134 DPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRA 198

  Fly   221 LVEELRQKNPQNNVKLTTIYPYMIDTGLCKNPRYRFPNLFKLIPADVAAGSIIEAQRQGL----E 281
            |.:||.... :..|:.:.:.|..|:||..|||.   .||...:..:    .::|....|:    :
Mouse   199 LTDELAALG-RTGVRTSCLCPNFINTGFIKNPS---TNLGPTLEPE----EVVEHLMHGILTEKQ 255

  Fly   282 EAAIPRHFVAAEKIGRLIPRKAMRL----VNDFFDTGV 315
            ...:|........:.|::|.:.:::    :|..||..|
Mouse   256 MIFVPSSIALLTVLERIVPERFLQVLKHRINVKFDAVV 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	adh_short	59..248	CDD:278532	69/188 (37%)
		NADB_Rossmann	60..287	CDD:304358	77/230 (33%)
Hsd17b11	NP_444492.1	adh_short	37..228	CDD:278532	70/191 (37%)
		17beta-HSDXI-like_SDR_c	38..277	CDD:187598	80/246 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S1933
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870