DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ldsdh1 and rdh20

DIOPT Version :9

Sequence 1:	NP_572436.1	Gene:	Ldsdh1 / 31726	FlyBaseID:	FBgn0029994	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_002933209.2	Gene:	rdh20 / 100489103	XenbaseID:	XB-GENE-22066217	Length:	316	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	77/256 - (30%)
Similarity:	136/256 - (53%)	Gaps:	7/256 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKNNGGKAFGYVCNVT 117
            :||    :.||||:|.|:||..||::||.||.::.||.:.:.|.:|.||::..|.:||.|.|:..
Frog    44 MDD----ICLITGSGGGIGKHFALEFAKKGAILVLWDSDPECNEETAKEVRRLGARAFTYTCDTG 104

  Fly   118 KREELIELAQKVRKEHGFIHVVVNNAGIMPCHPLLEHTENEIRLMYEINVLSHFWIIQAFLPDMI 182
            .|:::.::|::||:|.|.:.:::|:........||...:.|:......|.|::||.::||||.|.
Frog   105 DRQQVYQVAERVRREVGDVTILLNHPSTGTGKSLLHCQDEELENALRTNCLANFWTVKAFLPRMN 169

  Fly   183 ERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEELRQKNPQNNVKLTTIYPYMIDTG 247
            :.|.|.::.::|..|||...|:..||...||..|:..||..||:.:. .:.||.|.:.||:.|..
Frog   170 QMNHGHVINVASYLGLFATANMEDYCTAHFATVGFHEALSHELKARR-ISGVKTTLLCPYLADIE 233

  Fly   248 LCKNPRYR--FPNLFKLIPADVAAGSIIEAQRQGLEEAAIPRHFVAAEKIGRLIPRKAMRL 306
            :..:.:.|  ...||..:.::..|...|...........:|:....|..:.:::|.:...|
Frog   234 MYSSFKIRKDLATLFTPLTSEYFARRAINGILTDQPMICMPKLLYLAAFLKQVLPWEVQEL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ldsdh1	NP_572436.1	adh_short	59..248	CDD:278532	66/188 (35%)
Ldsdh1	NP_572436.1	NADB_Rossmann	60..287	CDD:304358	71/228 (31%)
rdh20	XP_002933209.2	17beta-HSDXI-like_SDR_c	47..291	CDD:187598	74/244 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020