DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1571 and Sdic1

DIOPT Version :9

Sequence 1:	NP_572435.1	Gene:	CG1571 / 31725	FlyBaseID:	FBgn0029993	Length:	651	Species:	Drosophila melanogaster
Sequence 2:	NP_524670.2	Gene:	Sdic1 / 43984	FlyBaseID:	FBgn0067861	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	90/365 - (24%)
Similarity:	146/365 - (40%)	Gaps:	53/365 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 KEVNFNDEEQTQ------RHRKKVEREDSWGEQVLSMIRTTMSVAEQNNTLNIYQNFFADLPPEL 141
            ||||...|||.|      ..::.|.|.....|:.||            ..::||.::......|.
  Fly   117 KEVNELSEEQKQMIILSENFQRFVVRAGRVIERALS------------ENVDIYTDYIGGGDSEE 169

  Fly   142 GHDIKMRFRARVANVFHD-LWLPARQLRSIEWMPNNSRQFMTQYTNHFAKGERLRPVTDEPFGGT 205
            .:|.:...|..:..||:| .|...|.:.|::|..:.....:..|.|:       ....:||.|..
  Fly   170 ANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNN-------EESPNEPDGVV 227

  Fly   206 NGFYVWDVK-NPLKPRITYDSKQQVSLAKICPKDENNMVGGTGLGQVCLW-GTFKGGLPIRNCPL 268
               .||:.| ....|...:..:..|........:.|.::|||..||:.|| ...:...||:..||
  Fly   228 ---MVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPL 289

  Fly   269 E-VSHRETTSALCWVHSKSNTEFYSGSLDGSIKYWDTRDLKMPMQELLLEPEPQERQSRMDSHGV 332
            . .:|......|..|.:::.....|.|.||.:..|....|..|...|    |.|:|||:  :..:
  Fly   290 SAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTL----ELQQRQSK--AIAI 348

  Fly   333 TVLEFEYTIPVRFIIGSDMGHVFVGNRKGMTPMETLLAHYQLFVGPVRSINR-----NPFFVKNF 392
            |.:.|........::||:.|:|:..:|.|:  ...:...|:..:||:..|:.     :|.|...|
  Fly   349 TSMAFPANEINSLVMGSEDGYVYSASRHGL--RSGVNEVYERHLGPITGISTHYNQLSPDFGHLF 411

  Fly   393 LVTG-DWRARIWSEEVKDSPSTMYFRKNAQILCGAWSTGR 431
            |.:. ||..::||  :||:.....|.:..     |||..|
  Fly   412 LTSSIDWTIKLWS--LKDTKPLYSFEQYI-----AWSPVR 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1571	NP_572435.1	WD40	210..462	CDD:295369	60/231 (26%)
		WD40	211..>488	CDD:225201	59/230 (26%)
		WD40 repeat	229..269	CDD:293791	12/40 (30%)
		WD40 repeat	277..325	CDD:293791	13/47 (28%)
		WD40 repeat	332..369	CDD:293791	8/36 (22%)
		WD40 repeat	379..415	CDD:293791	11/41 (27%)
		WD40 repeat	422..447	CDD:293791	4/10 (40%)
Sdic1	NP_524670.2	Dynein_IC2	23..51	CDD:288403
		NtpH	108..>178	CDD:225368	17/72 (24%)
		WD40	196..>445	CDD:295369	67/274 (24%)
		WD40	<196..442	CDD:225201	65/270 (24%)
		WD40 repeat	196..245	CDD:293791	11/58 (19%)
		WD40 repeat	251..289	CDD:293791	10/37 (27%)
		WD40 repeat	298..337	CDD:293791	10/42 (24%)
		WD40 repeat	349..386	CDD:293791	8/38 (21%)
		WD40 repeat	393..435	CDD:293791	11/43 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435279
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1587
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840