Protein Alignment CG1571 and Dync1i1

DIOPT Version :10

• Sequence 1: NP_572435.1
• Gene: CG1571 / 31725
• FlyBaseID: FBgn0029993
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001396540.1
• Gene: Dync1i1 / 13426
• MGIID: 107743
• Length: 645
• Species: Mus musculus
• Alignment Length: 504
• Identity: 112/504 - (22%)
• Similarity: 187/504 - (37%)
• Gaps: 57/504 - (11%)

  Fly    20 RFQDRNELMVSVHPSGRQRLKYIMANPSE-KSTQLSRQMALTVMETENVTLDQHGMYHYEGGWPK 83
            :.|..:||...:|..|..::..:...|.| .|.....|..|...::|....|:. |...:.|...
Mouse   134 QLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEE-MVEPKIGHDS 197

  Fly    84 EVNFNDEEQTQRH---RKKVEREDS---WGEQVLSMIRTTMSVAEQ--NNTLNIYQNFFADLPPE 140
            |:...:::|..:.   |:..|.|..   ..|:.|.....|:.|.|:  ....:|:.::......|
Mouse   198 ELENQEKKQETKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEE 262

  Fly   141 LGHDIKMRFRARVANVFHD-LWLPARQLRSIEWMPNNSRQFMTQYTNHFAKGERLRPVTDEPFGG 204
            ...|::..........|:| .|...|.:..::|........:..|:|:          .|.|...
Mouse   263 KDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNN----------EDAPHEP 317

  Fly   205 TNGFYVWDVK-NPLKPRITY---DSKQQVSLAKICPKDENNMVGGTGLGQVCLW-GTFKGGLPIR 264
            .....||::| ....|...:   .|...|..|:..|   |.:||||..||:.|| .......|::
Mouse   318 DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHP---NLVVGGTYSGQIVLWDNRSHRRTPVQ 379

  Fly   265 NCPLE-VSHRETTSALCWVHSKSNTEFYSGSLDGSIKYWDTRDLKMPMQELLLEPEPQERQSRMD 328
            ..||. .:|......:..|.:::.....:.|.||.:..|....|..|.:.:.|.      .::..
Mouse   380 RTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELV------YNKSK 438

  Fly   329 SHGVTVLEFEYTIPVRFIIGSDMGHVFV----GNRKGMTPMETLLAHYQLFVGPVRSINRN---- 385
            ...||.:.|.......|::||:.|.|:.    |::.|:.  |....|.    |||..||.:
Mouse   439 PVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQ----GPVTGINCHMAVG 497

  Fly   386 PFFVKNFLVTG--DWRARIWSEEVKDSPSTMYFRKNAQILCGA-WSTGRCSLFVTGDINGVVDFW 447
            |....:..||.  ||..::|:  .|.:.....|..||..:... ||....:||...|..|.:|.|
Mouse   498 PIDFSHLFVTSSFDWTVKLWT--TKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLW 560

  Fly   448 DLLLHHRKPIRSVDFKVAIA--DLVFRPEGDLLAIGLKNGDTHIMTLDE 494
            :|......|..||..:.|.|  .:.:...|..:|:|...|...|..:.|
Mouse   561 NLNSDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGE 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1571	NP_572435.1	WD40	210..462	CDD:475233	68/268 (25%)
		WD40 repeat	229..269	CDD:293791	14/40 (35%)
		WD40 repeat	277..325	CDD:293791	8/47 (17%)
		WD40 repeat	332..369	CDD:293791	11/40 (28%)
		WD40 repeat	379..415	CDD:293791	10/41 (24%)
		WD40 repeat	422..447	CDD:293791	7/25 (28%)
Dync1i1	NP_001396540.1	Dynein_IC2	143..173	CDD:463291	6/29 (21%)
		WD40 repeat	291..337	CDD:293791	9/55 (16%)
		WD40	<318..607	CDD:441893	75/305 (25%)
		WD40 repeat	346..385	CDD:293791	15/41 (37%)
		WD40 repeat	393..434	CDD:293791	8/46 (17%)
		WD40 repeat	442..481	CDD:293791	11/40 (28%)
		WD40 repeat	488..529	CDD:293791	9/42 (21%)
		WD40 repeat	535..573	CDD:293791	10/37 (27%)
		WD40 repeat	581..607	CDD:293791	5/25 (20%)