Protein Alignment Upf2 and upf2

DIOPT Version :9

• Sequence 1: NP_572434.1
• Gene: Upf2 / 31724
• FlyBaseID: FBgn0029992
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: NP_001121475.1
• Gene: upf2 / 100158573
• XenbaseID: XB-GENE-6454322
• Length: 1265
• Species: Xenopus tropicalis
• Alignment Length: 1312
• Identity: 477/1312 - (36%)
• Similarity: 705/1312 - (53%)
• Gaps: 205/1312 - (15%)

  Fly     4 NDSATTDSEVSTPPSSRKDLADGVAEGDNDNDIDTGDTDANADEDVDAAAAIALEAEEREELQQF 68
            :|....|.|..:            :||.|..|   .......:|:.....|.||..:|::|..|.
 Frog    77 DDQVKADDEQQS------------SEGKNQED---EIKKKQEEEEAHQREAAALHIKEKDEANQL 126

  Fly    69 ISELREKIESKRQLRL--QNSTIELPGEEYFAKLDSNLKKNTAFVKKLKLFTATQLDGLLREISA 131
            ..|..|:..::::||.  ||:....|.|.:|::|||:||||||||||||..|..|.|.|..:.::
 Frog   127 HQEAWERHHTRKELRSKNQNAPENRPEESFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNS 191

  Fly   132 LNLSKYISEICAALVEAKLKMTDVPAVVTLASRLHCTYADFDVHFLEAWQKALNIKATEKIGNPS 196
            |||||||:|..|::||||||::||...|.|.|..|..||||....|:.|:|....:..||..|.:
 Frog   192 LNLSKYIAEAAASIVEAKLKISDVNCAVHLCSLFHQRYADFAQSLLQVWKKHFEARKEEKTPNIT 256

  Fly   197 KLRVDLRLFAELVSSGVIQMKPGLAQLGVVLVHLIALDKDDHSNFSIILSFCRHCGEEYAGLVPQ 261
            |||.|||..|||...|:...|.||:.:...|.::|..|::.|::.|:::|||||||::.|||||:
 Frog   257 KLRTDLRFIAELTIIGIFTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPR 321

  Fly   262 KMQQLATKYGVEVPKSDFLTADKQLNLRTMLKGYFKALCKHVLAEQAELMNMTKNIRRTMECKGE 326
            |::..|.||.:..|.|:.::.:||...:.:||.||.:|.||:..:..||.|:.:..||.:..|||
 Frog   322 KVKCAAEKYNLNFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNIERQNRRILHTKGE 386

  Fly   327 ISTEKREKCELMQAGFDKLLASAQSLSELLGEPLPEL-----AKESEG-----CNPGTVIDNMLD 381
            :|.::.::.|.....:.|||||.|||::||.|.:|||     |.|..|     ..||...|..|:
 Frog   387 LSEDRHKQYEEFATSYQKLLASCQSLADLLDENMPELPQDKPAPEEHGPGIDIFTPGKPGDYDLE 451

  Fly   382 SASFGVLDPWGDEETRAFYTDLPDLRQFLP-------------------NFSAPK-VDLETLEEP 426
            .   |:   |.||:.|.||.:|.||:.|:|                   :|...| .|:.|.||
 Frog   452 G---GI---WEDEDARNFYENLIDLKAFVPAILFKDNEKNSQSKETGKDSFKDSKEKDVSTTEE- 509

  Fly   427 SELTEEAIDANLDAEMDLDDPPSTTSDTTPENPIEEQPTTPVAAAEDLKPQKMGNALMELGRQQQ 491
            .||..|.:|.| |..|:|:....                     |||| .:|:      |..|:|
 Frog   510 LELELETLDIN-DEGMELEGAED---------------------AEDL-TKKL------LDEQEQ 545

  Fly   492 QQSQLNQNPIQIQNQMRQQFDGFLVNLFNCVNKELIDSAAIEFLLNFNTKHQRKKLTRTIFSVQR 556
            :..:.:..     :.::...|.|:..|.||||::|||.||::|.:|.|||..|:||.|.:|.|.|
 Frog   546 EDEEASTG-----SHLKLIVDAFIQQLPNCVNRDLIDKAAMDFCMNMNTKANRRKLVRALFIVPR 605

  Fly   557 TRLDILPYLSRFVAIVHMCNTDVATDLAELLRKEFKWHIHKKNQLNIETKLKIVRFIGELVKFGL 621
            .|||:||:.:|.||.:|.|.:|||.||..:|:.:|::|:.||:|:|||||.|.|||||||.||.:
 Frog   606 QRLDLLPFYARLVATLHPCMSDVAEDLCSMLKGDFRFHVRKKDQINIETKNKTVRFIGELAKFKM 670

  Fly   622 FKKFDALGCLKMLLRDFQHHQIEMACAFVEVTGVYLYNCRDARLLMNVFLDQMLRLKTATAMDSR 686
            |.|.|.|.||||||.||.||.|||||..:|..|.:|:...|:.|..:|.|:||:|.|.|..:|:|
 Frog   671 FSKTDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPDSHLRTSVLLEQMMRKKQAMHLDAR 735

  Fly   687 HAAQIESVYYLVKPPESSKREPMVRPAMHEYIRYLIFEELCKQNVDRCIKMLRRIDWQDPETNCY 751
            :...:|:.||...||.:.|.....||.:.||||.|::::|.|...::.::.:|::.|||||...|
 Frog   736 YVTMVENAYYYCNPPPAEKTVKKKRPPLQEYIRKLLYKDLSKVTTEKVLRQMRKLSWQDPEVKDY 800

  Fly   752 AIKCLSKAYLLRFQLIRCLADLVSGLSSYQPRAVTIVIDNVFEDIRAGLEIHSPRMAQRRIAMAK 816
            .|.|:...:.:::..|.|:|:|::||..||......|:|.|.||||.|:|::.|:..||||:.||
 Frog   801 VICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAK 865

  Fly   817 YLGEMYNYKLVESTNILNTLYSIISLGVSNDQNVVSPLDPPDSLFRLKLACMLLDTCAPYFTSQA 881
            :|||:|||::|||..|..||||.||.||::|.: .||||||:.|||::|.|.:||||..||...:
 Frog   866 FLGELYNYRMVESAVIFRTLYSFISFGVNSDGS-PSPLDPPEHLFRIRLVCTILDTCGQYFDRGS 929

  Fly   882 TRKKLDYFLVFFQHYYWFKKSHPVFSKTENTSDLFPILMDHTYRDCLLNVRPKLKIYKSLEQAKA 946
            :::|||.|||:||.|.|:|||..|::|...    |||.:|:...|.|..:|||:|:..||.::..
 Frog   930 SKRKLDCFLVYFQRYVWWKKSLDVWTKDHP----FPIDIDYMISDTLELLRPKMKLCASLNESVR 990

  Fly   947 AIDHLQEKLYPQLKTTNNAQDPSLGT------ISEISEIDEGG--TDEDSG------------SS 991
            .:..|:.:...:|...|:.:.....|      ..:..|.:|.|  |:|.||            |.
 Frog   991 QVQDLEREFLTKLGLMNDKESKHSMTEGDHLVYEDDDEEEEAGAETEEQSGNESEMNEQEEDASE 1055

  Fly   992 NDQRERQVSGQEQDQSNDW-----TENEAEPP----------LPPLPPPEKSKEDLEFEQLYEKM 1041
            |::.||:   :|::::.|:     .|||.:..          :..:|    ..||.:|.|..:||
 Frog  1056 NEEDERE---EEEEENTDYMTDSNKENETDEENTEVMIKGGGIKHVP----CAEDEDFIQALDKM 1113

  Fly  1042 TTDSYQERLKEPIKATAKDIPVPMMARLQKKSYDQITGAQTIGPGINNMSQISKSVPNQDGTPGS 1106
            ..::.|:|..|.:|....|:.:|:..:.|.|.          ||.:                  |
 Frog  1114 MLENLQQRSGESVKVHQLDVAIPLHLKSQLKK----------GPAM------------------S 1150

  Fly  1107 PGADSPDGNGKSGGGVGGSDVGAAGAAGASGATSVPFVLMVRGHKGGKQQFKSFVAPSDSHLATN 1171
            .|...|:                      ||.| :|||::.|  :|.|||||....|..|.||.|
 Frog  1151 TGEVDPE----------------------SGDT-MPFVMLTR--RGNKQQFKILNVPMSSQLAAN 1190

  Fly  1172 LKRQEQMIREEKEKVKRLTLNITERIEEEDYQESLMPPQHRNFTQSYYQKP--------NKHKFK 1228
            ...|:|..:||:.::|:|||:|.||.|:|||||.|         ||..|:|        .:.:::
 Frog  1191 HWSQQQAEQEERMRMKKLTLDINERQEQEDYQEML---------QSLAQRPAPANTNRERRPRYQ 1246

  Fly  1229 HQKGAPDADLIF 1240
            |.||||:|||||
 Frog  1247 HPKGAPNADLIF 1258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf2	NP_572434.1	MIF4G	104..300	CDD:214713	89/195 (46%)
		MIF4G	518..701	CDD:214713	94/182 (52%)
		MIF4G	716..934	CDD:280935	98/217 (45%)
		Upf2	980..1192	CDD:281974	60/240 (25%)
upf2	NP_001121475.1	MIF4G	164..359	CDD:214713	89/194 (46%)
		MIF4G	563..750	CDD:214713	95/186 (51%)
		MIF4G	768..978	CDD:397130	95/214 (44%)
		Upf2	1088..1211	CDD:397938	45/179 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	202	1.000	Domainoid score	I2937
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6101
Inparanoid	1	1.050	761	1.000	Inparanoid score	I549
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D653534at2759
OrthoFinder	1	1.000	-	-		FOG0005166
OrthoInspector	1	1.000	-	-		oto102463
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3685
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060