DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fs(1)h and BAZ1B

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_001357331.1	Gene:	BAZ1B / 9031	HGNCID:	961	Length:	1483	Species:	Homo sapiens

Alignment Length:	287	Identity:	66/287 - (22%)
Similarity:	101/287 - (35%)	Gaps:	103/287 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 GVDAVIPP-----QQPAKIKKGVKRKADTTTPTANAFESPYTQMDSKSAKIATRRESNRQVIGKK 440
            |..:||||     ::|.|.....:|......|..:|      ::|  ...:.|:|.|.||
Human  1290 GKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDA------EVD--ELVLQTKRSSRRQ----- 1341

  Fly   441 GSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYK 505
                                                 |..|:.|.|||.::...:   ::|||.:
Human  1342 -------------------------------------SLELQKCEEILHKIVKYR---FSWPFRE 1366

  Fly   506 PV---DAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYN-PPDHDV 566
            ||   :||     ||:|:|..|||..||:.|.....|:|..||..|::.:|||...|| ...|.:
Human  1367 PVTRDEAE-----DYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVL 1426

  Fly   567 VAMGRKLQDVFEMRYANIPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHD 631
            ..|.:..|.:..:.:.::|                                 ||.|......|.
Human  1427 SCMVKTEQCLVALLHKHLP---------------------------------GHPYVRRKRKKF- 1457

  Fly   632 ASDSSSEDSSDTENESNSDEERSARLK 658
             .|..:||..|:|.|: ..:.|..|.|
Human  1458 -PDRLAEDEGDSEPEA-VGQSRGRRQK 1482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	50/214 (23%)
		Bromo_Brdt_II_like	481..581	CDD:99930	35/103 (34%)
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
BAZ1B	NP_001357331.1	WAC_Acf1_DNA_bd	21..120	CDD:337781
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..212
		C motif	207..213
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	302..333
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	379..432
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	446..470
		DDT	604..668	CDD:214726
		DUF5401	<664..>877	CDD:340095
		WHIM1	727..767	CDD:339506
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	788..817
		WSD	898..1025	CDD:317927
		PHD_BAZ1B	1186..1231	CDD:277098
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1237..1326		10/41 (24%)
		Bromo_WSTF_like	1344..1440	CDD:99937	35/103 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1455..1483		10/31 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810