DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fs(1)h and RSC1

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_011570.1	Gene:	RSC1 / 852947	SGDID:	S000003288	Length:	928	Species:	Saccharomyces cerevisiae

Alignment Length:	221	Identity:	48/221 - (21%)
Similarity:	73/221 - (33%)	Gaps:	82/221 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LQYLIKTVMKVIWKHHFS-------WPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYW 96
            ||.|:||....::  |..       :|....:..|| ..|||:.||:.|:.:.|:||||.  :|.
Yeast     9 LQKLLKTQYDAVF--HLKDENGIEIYPIFNVLPPKK-EYPDYYIIIRNPISLNTLKKRLP--HYT 68

  Fly    97 SAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKI------------------------ 137
            |.::.:.||..:..|...||.....:...|..||.....||
Yeast    69 SPQDFVNDFAQIPWNAMTYNAKDSVIYKYAILLESFIKGKIVHNIRKHYPEVTYPSLGRIPEIFA 133

  Fly   138 ESMPKEELELEPVTAKGGKKK--------------------------------QRAPATPKSSSG 170
            |||...:|...|:..:...:|                                :.:||.|
Yeast   134 ESMQPSDLSSNPINTQENDEKAGLNPEMKMAFAKLDSSITERKPTNQDYRMQQKNSPAFP----- 193

  Fly   171 GAGASTGSGTSSAAVTSGPGSGSTKV 196
                     |.||::|..|.:..|.|
Yeast   194 ---------THSASITPQPLASPTPV 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929	33/131 (25%)
		COG5076	387..>593	CDD:227408
		Bromo_Brdt_II_like	481..581	CDD:99930
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
RSC1	NP_011570.1	Bromo_Rsc1_2_I	8..113	CDD:99952	32/108 (30%)
RSC1	NP_011570.1	COG5076	115..463	CDD:227408	16/110 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900