DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fs(1)h and GTE4

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_001184922.1	Gene:	GTE4 / 837133	AraportID:	AT1G06230	Length:	766	Species:	Arabidopsis thaliana

Alignment Length:	782	Identity:	158/782 - (20%)
Similarity:	223/782 - (28%)	Gaps:	371/782 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 VNAANAVQAYVNAGVSVGVDAVIP-------PQQPAKIKKGVKR----------------KADTT 405
            :.|.|..:..:|.|::.|...::.       |::..:..:.|.:                :.:..
plant   308 IGAYNDSRVLINTGINNGGGRILSGFASAGLPREVIRAPRPVNQLSISVLENTQGVNEHVEKEKR 372

  Fly   406 TPTANAF----------ESPYTQMDSKSAKIATRRESNRQVIGKKGSGYNMSPLGVSGVPGLGGL 460
            ||.||.|          :.|..:.:.||      :.|:::..|..|.|:.
plant   373 TPKANQFYRNSEFLLGDKLPPAESNKKS------KSSSKKQGGDVGHGFG--------------- 416

  Fly   461 VAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPM 525
                 ||..|.||          |:.:|:.|...||   .|.|..|||.:.|||.||:.||:.||
plant   417 -----AGTKVFKN----------CSALLERLMKHKH---GWVFNAPVDVKGLGLLDYYTIIEHPM 463

  Fly   526 DLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDEPVA 590
            ||||:|..:....|||..|||.||||.|.|...|||...||..|...|..:||.|:|.|
plant   464 DLGTIKSALMKNLYKSPREFAEDVRLTFHNAMTYNPEGQDVHLMAVTLLQIFEERWAVI------ 522

  Fly   591 NAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDTENESNSDEERSA 655
                                                                     .:|..|..
plant   523 ---------------------------------------------------------EADYNREM 530

  Fly   656 RLKMLESKLLGLQEEIRKLSEEASAKKKAKKKLKEKKKSIGGGSGSGSASHHCHATGGGANAGGA 720
            |.                                                    .||...|
plant   531 RF----------------------------------------------------VTGYEMN---- 539

  Fly   721 GGPGSGGHGSVSVPGGVGSLGPGGAGGANLNALLGGSLVGHGGAAVAGGVPNVGALHSQVHDVAM 785
                      :..|.....|||                        ....|.:...:
plant   540 ----------LPTPTMRSRLGP------------------------TMPPPPINVRN-------- 562

  Fly   786 AFSQMAGGGAAAGAGFGAGVTAAGASSGGKAGTLAGALAAGAAAGAGGTTAGSGSSKGAKSKGGR 850
                                |...|....:..|               ||.|
plant   563 --------------------TIDRADWSNRQPT---------------TTPG------------- 579

  Fly   851 GAKGSGAGGVGASNNAAAGNAAGGAAGAAAGAGSVGGVGGAGAAGGGNASKRAKGSSSAGAGGGV 915
                                                                 :..:||...|
plant   580 -----------------------------------------------------RTPTSATPSG-- 589

  Fly   916 GGANASAGGAGARGSSKKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQ 980
                        |..:.|||       ...|...:.|:|:||::||..:..||.|||..:|.|:.
plant   590 ------------RTPALKKP-------KANEPNKRDMTYEEKQKLSGHLQNLPPDKLDAIVQIVN 635

  Fly   981 NREPS--LRDSNPDEIEIDFETLKPSTLRELESYVASCLRKKTHKKPSGKSKDEQMAEKKQELEK 1043
            .|..:  |||   :|||:|.:::.|.||.||:.:|.: .:|...||   |.|.|...:.:.|.|:
plant   636 KRNTAVKLRD---EEIEVDIDSVDPETLWELDRFVTN-YKKGLSKK---KRKAELAIQARAEAER 693

  Fly  1044 RLQDVTGQLGASKK-------TAKKDESASSKVEAVQPANPVSSSSSSSDSSSSSSSDSSSSDSS 1101
            ..|.......|:.:       ||||........:..:..|..|.|||||.|||||||..|.||||
plant   694 NSQQQMAPAPAAHEFSREGGNTAKKTLPTPLPSQVEKQNNETSRSSSSSSSSSSSSSSDSDSDSS 758

  Fly  1102 DS 1103
            .|
plant   759 SS 760

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	67/238 (28%)
		Bromo_Brdt_II_like	481..581	CDD:99930	45/99 (45%)
		BET	951..1015	CDD:293640	27/65 (42%)
		BRD4_CDT	<2026..2046	CDD:293710
GTE4	NP_001184922.1	PRK04335	46..>179	CDD:235285
		Bromo_plant1	421..519	CDD:99938	48/110 (44%)
		BET	607..669	CDD:407211	27/64 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	94	1.000	Domainoid score	I2516
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	1	1.000	-	-		mtm8402
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X197
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.770