DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fs(1)h and GTE7

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_201366.3	Gene:	GTE7 / 836689	AraportID:	AT5G65630	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	729	Identity:	145/729 - (19%)
Similarity:	216/729 - (29%)	Gaps:	305/729 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   441 GSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYK 505
            |...::.|........:.||......|.:..::::.|:..|.:|::||.:|...|   :||.|..
plant   130 GEKNDLGPKKKKQKKNVSGLKRSNQFGPSDPESEKLLAGMLNTCSQILVKLMKHK---WAWVFNT 191

  Fly   506 PVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMG 570
            |||...|||||||.::||||||||||..:|...|.|..:||.||||.|.|...|||...||..|.
plant   192 PVDVVGLGLHDYHQVVKKPMDLGTVKLNLDKGFYVSPIDFATDVRLTFDNAMTYNPKGQDVYFMA 256

  Fly   571 RKLQDVFEMRYANIPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDA--- 632
            .||.|.|:                                          |....:..|.:|
plant   257 DKLLDHFD------------------------------------------GMFNPAFKKFEAQQL 279

  Fly   633 --SDSSSEDSSD-----TENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKKAKKKLKE 690
              :.|||....|     .:.:.|.:....|              ..||.:|:.|..||.
plant   280 KLTGSSSRPEPDFKPDFKQRQWNQNPPMVA--------------NPRKGTEQISIAKKL------ 324

  Fly   691 KKKSIGGGSGSGSASHHCHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGANLNALLG 755
                                                  .||..|                ...|.
plant   325 --------------------------------------DSVKPP----------------QPTLP 335

  Fly   756 GSLVGHGGAAVAGGVPNVGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSGGKAGTLA 820
            ..||...........|....:..::........|:
plant   336 PQLVEPSRVQSPSPPPPPPVIQPELPQPQPPPPQL------------------------------ 370

  Fly   821 GALAAGAAAGAGGTTAGSGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGAAAGAGSV 885
             .:...|....      |..|||.|.|
plant   371 -EIEVEAPPDV------SEVSKGRKGK-------------------------------------- 390

  Fly   886 GGVGGAGAAGGGNASKRAKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMNFDSEEEDTAK 950
                                                          ..||       ..::...:
plant   391 ----------------------------------------------LPKP-------KAKDPNKR 402

  Fly   951 PMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVAS 1015
            .|:.:||.:|.:::..||.:|||:::.|::.|...|.... ||||:|.|.:...||.||:.:|.:
plant   403 LMTMEEKSKLGMNLQDLPPEKLGQLLQILRKRNGHLAQDG-DEIELDIEAVDNETLWELDRFVTN 466

  Fly  1016 CLRKKTHKKPSGKSKDEQMAEKKQELEKRLQDVTGQLGASKKTAKKDESASSKVE---------- 1070
                  :||.:.|.|.:..........:.:..| .::|:::|..::.::....|:
plant   467 ------YKKMASKIKRQGFIRNVSTPPRNMASV-AEMGSAEKRTRRGDAGEEDVDIGEDIPIEDY 524

  Fly  1071 ----------AVQPANPVSSSSSSSDSSSSSSSDSSSSDSSDSEAVLVIPAPTGDGDERPPRKKK 1125
                      ||..|  .||.||||.|||||...||||||             |.|.     ...
plant   525 PSVEIERDGTAVAAA--ASSGSSSSGSSSSSGGSSSSSDS-------------GSGG-----SSS 569

  Fly  1126 SRDSNGSNVNNPSI 1139
            ..||:..:|.:|.:
plant   570 GSDSDADSVQSPFV 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	56/151 (37%)
		Bromo_Brdt_II_like	481..581	CDD:99930	50/99 (51%)
		BET	951..1015	CDD:293640	23/63 (37%)
		BRD4_CDT	<2026..2046	CDD:293710
GTE7	NP_201366.3	Bromo_plant1	169..267	CDD:99938	51/142 (36%)
GTE7	NP_201366.3	BET	404..466	CDD:374956	23/62 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	94	1.000	Domainoid score	I2516
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8402
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X197
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.770