DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fs(1)h and GTE2

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_196617.2	Gene:	GTE2 / 830920	AraportID:	AT5G10550	Length:	581	Species:	Arabidopsis thaliana

Alignment Length:	761	Identity:	152/761 - (19%)
Similarity:	232/761 - (30%)	Gaps:	314/761 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 KIKKGVKRKADTTTPTANAFESPYTQMDSKSAKIATRRESNRQVIGKKGSGYNMSPLGVSGVPGL 457
            :|:.|........|..|.:|......:..|..|  |:::       |.|.|...|....:..|.|
plant   102 RIESGTFVSGSVYTTQARSFAGETNDVGVKKTK--TKKK-------KIGHGQKRSNPFATDEPSL 157

  Fly   458 GGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIK 522
            ...||..:....|.|:      .:.:|.:||.:|...|   ::|.|..|||...|||||||.|:.
plant   158 KRHVALDLMSEKVLKS------MMTTCGQILVKLMKHK---WSWVFLNPVDVVGLGLHDYHRIVD 213

  Fly   523 KPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDE 587
            |||||||||..::...|:|..:||:||||.|||...|||...||..|..||...|::.:
plant   214 KPMDLGTVKMNLEKGLYRSPIDFASDVRLTFTNAMSYNPKGQDVYLMAEKLLSQFDVWF------ 272

  Fly   588 PVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKH----------DASDSSSEDSSD 642
                                                 :.:||.          .:|....||:..
plant   273 -------------------------------------NPTLKRFEAQEVKVMGSSSRPGPEDNQR 300

  Fly   643 TENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKKAKKKLKEKKKSIGGGSGSGSASHH 707
            ..|::|                  :.|..||..|:.|..||..
plant   301 VWNQNN------------------VAENARKGPEQISIAKKLD---------------------- 325

  Fly   708 CHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGANLNALLGGSLVGHGGAAVAGGVPN 772
                                    ||...:.:|.|                            |.
plant   326 ------------------------SVKPLLPTLPP----------------------------PP 338

  Fly   773 VGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSGGKAGTLAGALAAGAAAGAGGTTAG 837
            |..:                                                         |...
plant   339 VIEI---------------------------------------------------------TRDP 346

  Fly   838 SGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGAAAGAGSVGGVGGAGAAGGGNASKR 902
            |......:..............|.||......|
plant   347 SPPPSPVQPPPPPSPPPQPVNQVEASLEVRETN-------------------------------- 379

  Fly   903 AKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKL 967
                                     :|...|.|.     ...::...:.|:.|||.:|.:::.:|
plant   380 -------------------------KGRKGKLPK-----PKAKDPNKREMTMDEKGKLGVNLQEL 414

  Fly   968 PGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKKTHKKPSGKSKDE 1032
            |.:|||:::.|::.|...| ..:.||||:|.|.|...||.||:.:|.:      ::|.:.|.|.:
plant   415 PPEKLGQLIQILRKRTRDL-PQDGDEIELDIEALDNETLWELDRFVTN------YRKMASKIKRQ 472

  Fly  1033 QMAEKKQELEKRLQDVTGQLGASKKTAKK-----------------DESASSKVE------AVQP 1074
            ...:......:.:..|| ::|:::|..:|                 ::..|.::|      |...
plant   473 GFIQNVSTPPRNMPPVT-EMGSAEKRGRKGGEAGEEDVDIGEDIPVEDYPSVEIERDGTAAAASG 536

  Fly  1075 ANPVSSSSSSSDSSSSSSSDSSSSDSSDSEAVLVIPAPTGDGDERP 1120
            .:..|.|.|||.|||||.|:|.||..|||:|..| .:|..:..|.|
plant   537 GSSSSGSFSSSGSSSSSDSESGSSSGSDSDADSV-QSPFVEAKEAP 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	65/199 (33%)
		Bromo_Brdt_II_like	481..581	CDD:99930	47/99 (47%)
		BET	951..1015	CDD:293640	25/63 (40%)
		BRD4_CDT	<2026..2046	CDD:293710
GTE2	NP_196617.2	Bromo_plant1	174..272	CDD:99938	47/100 (47%)
GTE2	NP_196617.2	BET	398..461	CDD:407211	25/63 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	94	1.000	Domainoid score	I2516
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8402
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X197
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.770