Protein Alignment fs(1)h and PBRM1

DIOPT Version :9

• Sequence 1: NP_001259321.1
• Gene: fs(1)h / 31722
• FlyBaseID: FBgn0004656
• Length: 2046
• Species: Drosophila melanogaster
• Sequence 2: XP_016862214.1
• Gene: PBRM1 / 55193
• HGNCID: 30064
• Length: 1734
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 104/630 - (16%)
• Similarity: 179/630 - (28%)
• Gaps: 310/630 - (49%)

  Fly    67 KLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEK 131
            |:..|||:.|||:|:|:.||.:|::|..|.|.....:|.:.:..|...||:||..|...|.:::|
Human   244 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 308

  Fly   132 VFLQKIESMPKEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTKV 196
            :|..|     |.|:|...: || ...:.|.|:                ..:||..:||
Human   309 IFYMK-----KAEIEHHEM-AK-SSLRMRTPS----------------NLAAARLTGP------- 343

  Fly   197 SVAASSAQQSGLQGATGAGGGSSSTPGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIPPIST 261
                     |..:|:.|.....:|.......:..||.::|..::...|:.|.
Human   344 ---------SHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESE------------- 386

  Fly   262 MPPHTVPGSTNTTTTAMAGGVGGPGAAGANPNAAALMASLLNAGQTGAYPGAPGQTAVNSSSLLD 326
                                           ..|||.|:....|::         .|.:.:|.:|
Human   387 -------------------------------EDAALAAARYEEGES---------EAESITSFMD 411

  Fly   327 GSTAAVAAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVGVDAVIPPQQP 391
            .|
Human   412 VS--------------------------------------------------------------- 413

  Fly   392 AKIKKGVKRKADTTTPTANAFESPYTQMDSKSAKIATRRESNRQVIGKKGSGYNMSPLGVSGVPG 456
                                  :|:.|
Human   414 ----------------------NPFYQ-------------------------------------- 418

  Fly   457 LGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLH------ 515
                                |.|.::||.....:|.::       |||          |
Human   419 --------------------LYDTVRSCRNNQGQLIAE-------PFY----------HLPSKKK 446

  Fly   516 --DYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFE 578
              ||:..||.|:.|..::.|:.|:||::......|:.|:|.|..:||.|:..:.....|||.|.:
Human   447 YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQ 511

  Fly   579 MRYANIPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDT 643
            .:...:                                          :.:.|..|..|..||.|
Human   512 AKKKEL------------------------------------------ARRDDIEDGDSMISSAT 534

  Fly   644 ENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKKAKKKL 688
            .:..::..:|:..    :|::|||    |:||.:.:.:|:..|.|
Human   535 SDTGSAKRKRNTH----DSEMLGL----RRLSSKKNIRKQRMKIL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929	26/72 (36%)
		COG5076	387..>593	CDD:227408	32/213 (15%)
		Bromo_Brdt_II_like	481..581	CDD:99930	28/107 (26%)
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
PBRM1	XP_016862214.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900