Protein Alignment fs(1)h and tbrd-1

DIOPT Version :10

• Sequence 1: NP_001259321.1
• Gene: fs(1)h / 31722
• FlyBaseID: FBgn0004656
• Length: 2046
• Species: Drosophila melanogaster
• Sequence 2: NP_651190.1
• Gene: tbrd-1 / 42823
• FlyBaseID: FBgn0039124
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 600
• Identity: 149/600 - (24%)
• Similarity: 228/600 - (38%)
• Gaps: 205/600 - (34%)

  Fly     2 SSSEPPPRYEPPVEPVNGIVQPPVIPPAERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAK 66
            :|::||||.||.::|||||||||||||..||||.||.|:.| |:|:..:|::.||:.|:.|||:.
  Fly     7 NSNQPPPRNEPYLQPVNGIVQPPVIPPPNRPGRRTNILEEL-KSVLNCLWRNRFSYHFRHPVDSV 70

  Fly    67 KLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEK 131
            .|.:||||.::|.|||:.||:|||.|.|||.|.|.::||..:|:||.:||..|..|....:.|.:
  Fly    71 SLGVPDYHAVVKHPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLME 135

  Fly   132 VFLQKIESMP-KEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTK 195
            .|..::||:. ..|:||:|   |..|:|::|..:...:|....|...|...|....|
  Fly   136 AFYMRMESIDLSTEVELKP---KSEKRKRKATESLDQASTSFSAPRASNNYSRQWLS-------- 189

  Fly   196 VSVAASSAQQSGLQGATGAGGGSSST---PGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIP 257
                                  |||:   |...||.          ||:...:..:..|  ||:.
  Fly   190 ----------------------SSSSWLCPPPMPGG----------VSSFNPSFRNFVG--PSLI 220

  Fly   258 PISTMPPHTVPGSTNTTTTAMAGGVGGPGAAGANP-NAAALMASLLNA-----GQTGAYPGAPGQ 316
            | |.||...|                       || .:...|:|::|.     .:|......|..
  Fly   221 P-SFMPDSLV-----------------------NPMQSMHPMSSMMNPIFKNNWETNEAMDPPPS 261

  Fly   317 TAVNSSSLLDGSTAAVAAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVG 381
            ..::...|  .|.||                          .:|:
  Fly   262 EPISYRPL--DSLAA--------------------------PLPS-------------------- 278

  Fly   382 VDAVIPPQQPAKIKKGVKRKADTTTPTANAFESPYTQMDSKSAKIATRRESNRQVIGKKGSGYNM 446
                 ||.:|..:          ..||....|||.:
  Fly   279 -----PPMEPMTL----------PWPTPAPVESPAS----------------------------- 299

  Fly   447 SPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEM 511
            ||......|           .:...|:.:::.:...| :.:||.:..:|.....|.|.:.
  Fly   300 SPPPAPNPP-----------IIICYKSLDRMIEKSHS-DHLLKSMVKRKRKQVTWAFNQA----- 347

  Fly   512 LGLHDY-----------HDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHD 565
                ||           ||..:| :|...::.::|:..::|...|.:.||.:|.|..:..|.|..
  Fly   348 ----DYWRRYSQNPDYDHDREEK-LDWKILQERLDSDNFESFDGFVSSVRKMFQNALRCFPEDGL 407

  Fly   566 VVAMGRKLQDVFEMR 580
            |....:|..::||.|
  Fly   408 VKVSVKKTNEIFEKR 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929	46/105 (44%)
		COG5076	387..>593	CDD:227408	37/204 (18%)
		Bromo_Brdt_II_like	481..581	CDD:99930	25/110 (23%)
		BET	951..1015	CDD:435704
		BRD4_CDT	<2026..2046	CDD:465349
tbrd-1	NP_651190.1	Bromodomain	39..143	CDD:445827	45/104 (43%)
		Mucin15	139..>291	CDD:406167	47/283 (17%)
		Bromodomain	328..423	CDD:445827	24/104 (23%)