Protein Alignment fs(1)h and Brd3

DIOPT Version :10

• Sequence 1: NP_001259321.1
• Gene: fs(1)h / 31722
• FlyBaseID: FBgn0004656
• Length: 2046
• Species: Drosophila melanogaster
• Sequence 2: NP_001421199.1
• Gene: Brd3 / 362092
• RGDID: 1308925
• Length: 742
• Species: Rattus norvegicus
• Alignment Length: 1143
• Identity: 408/1143 - (35%)
• Similarity: 487/1143 - (42%)
• Gaps: 459/1143 - (40%)

  Fly     8 PRYEPPVEPVNGIVQPPVIPPAERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPD 72
            |....||.|     .||.:....:|||.||||||:...|:|.:|||.|:|||.|||||.||||||
  Rat    13 PAVPGPVNP-----PPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPD 72

  Fly    73 YHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKI 137
            ||||||.|||||||||||||||||||.|.:|||||||.|||:||||.:|:|:|||.|||:||||:
  Rat    73 YHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKV 137

  Fly   138 ESMPKEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTKVSVAASS 202
            ..||:||:||.|...||..:|      |.:.:..|||......||  |:..|...:...:|
  Rat   138 AQMPQEEVELLPPAPKGKGRK------PAAGAQNAGAQQMGAVSS--VSPAPPFQNIPPTV---- 190

  Fly   203 AQQSGLQGATGAGGGSSSTPGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIPPISTMPPHTV 267
                            |.||          .|||.||..:...|:|.....|:.||    ||.|
  Rat   191 ----------------SQTP----------VIAATPVPTITANVTSVPVPPPAAPP----PPAT- 224

  Fly   268 PGSTNTTTTAMAGGVGGPGAAGANPNAAALMASLLNAGQTGAYPGAPGQTAVNSSSLLDGSTAAV 332
                                                       |..|
  Rat   225 -------------------------------------------PIVP------------------ 228

  Fly   333 AAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVGVDAVIPPQQPAKIKKG 397
                                                                |:||..|...|||
  Rat   229 ----------------------------------------------------VVPPTPPVVKKKG 241

  Fly   398 VKRKADTTTPTANAF-----ESPYTQMDSKSAKIATRRESNRQVI--GKKGSGYNMSPLGVSGVP 455
            |||||||||||.:|.     |||....:.|.||:..||||..:.|  .||       .|....||
  Rat   242 VKRKADTTTPTTSAITASRSESPPPLSEPKQAKVVARRESGGRPIKPPKK-------DLEDGEVP 299

  Fly   456 GLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDI 520
            ...|             .|.|||:.|:.|:.||:|:.||||:.||||||||||||.|.|||||||
  Rat   300 QHAG-------------KKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDI 351

  Fly   521 IKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 585
            ||.||||.|||||||:|||..|..||||:||:|:||||||||||:||||.||||||||||:|.:|
  Rat   352 IKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 416

  Fly   586 DEP-------------VANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDASDSSS 637
            |||             |:..|.                                      |..||
  Rat   417 DEPMEVPALPAPTAPIVSKGAE--------------------------------------SSRSS 443

  Fly   638 EDSSDTENESNSDEERSARLKMLES-----------------KLLGLQEEIRKLSEEA--SAKKK 683
            |:||.....|:|:|||:.||..|:.                 :|..:.|::..||:..  ..|||
  Rat   444 EESSSDSGSSDSEEERATRLAELQEQTGCGAFQDQLLNVSSVQLKAVHEQLAALSQAPVNKPKKK 508

  Fly   684 AKKKLKEKKKSIGGGSGSGSASHHCHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGA 748
            .:||.|||||.   ........|.
  Rat   509 KEKKEKEKKKK---DKEKEKEKHK----------------------------------------- 529

  Fly   749 NLNALLGGSLVGHGGAAVAGGVPNVGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSG 813
                                                                             
  Rat   530 ----------------------------------------------------------------- 529

  Fly   814 GKAGTLAGALAAGAAAGAGGTTAGSGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGA 878
                                          |||:..:.||.:.|........|
  Rat   530 ------------------------------AKSEEEKKAKAAPAAKQAQQKKA------------ 552

  Fly   879 AAGAGSVGGVGGAGAAGGGNASKRAKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMNFDS 943
                                .:|:|..:::|......||..|||                 ::||
  Rat   553 --------------------PTKKANSTTTASRQLKKGGKQASA-----------------SYDS 580

  Fly   944 EEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRE 1008
            |||:...|||||||||||||||:|||:||||||||||:||||||||||||||||||||||:||||
  Rat   581 EEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRE 645

  Fly  1009 LESYVASCLRKK-------THKKPSGKSKDEQMAEKKQELEKRLQDVTGQLGASKKTAKKDESAS 1066
            ||.||.|||:||       :.||.:.|||:|...|||:|||||||||:|||. |||..||::|.|
  Rat   646 LERYVKSCLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELEKRLQDVSGQLN-SKKPTKKEKSGS 709

  Fly  1067 SKVEAVQPANPVSSSSSSSDSSSSSSSDSSSSDSSDSE 1104
            :     ....|...|||||..|:||||..|||||||||
  Rat   710 A-----PSGGPSRLSSSSSSESASSSSSGSSSDSSDSE 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929	79/105 (75%)
		COG5076	387..>593	CDD:227408	122/225 (54%)
		Bromo_Brdt_II_like	481..581	CDD:99930	76/99 (77%)
		BET	951..1015	CDD:435704	58/63 (92%)
		BRD4_CDT	<2026..2046	CDD:465349
Brd3	NP_001421199.1	Bromo_Brdt_I_like	34..140	CDD:99929	79/105 (75%)
		Bromo_Brdt_II_like	311..412	CDD:99930	76/100 (76%)
		BET	588..652	CDD:435704	58/63 (92%)