DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fs(1)h and spt7

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_596356.2	Gene:	spt7 / 2540408	PomBaseID:	SPBC25H2.11c	Length:	992	Species:	Schizosaccharomyces pombe

Alignment Length:	330	Identity:	74/330 - (22%)
Similarity:	132/330 - (40%)	Gaps:	79/330 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 KIKKGVKRKADTTTPTANAFESPYTQMD-----SKSAKIATRRESNR---QVIGKKGSGYNMSPL 449
            ::|| .:.:.||:||..::|::..:.:|     |.::|..:...|.:   |.:....|..|.:..
pombe   226 EVKK-FEDEEDTSTPNTSSFQNNSSSLDLSDNLSLNSKFGSLTSSFKYLLQYLEGNRSKINATDA 289

  Fly   450 GVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSK------KHSGYAWPFYKPV- 507
            .|..:..            .|.|||.|.::..:...|.|.|...|      .::.::..|...|
pombe   290 DVKQLLS------------DVKKNKSKWANDQRIGQEELYEAAEKVVLELRSYTEHSLAFLTKVS 342

  Fly   508 --DAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNP-PDHDVVAM 569
              ||.     ||:.:||:||||||:.|.:.|..|.|..||..|:.||::||:.||. |||.:...
pombe   343 KRDAP-----DYYTVIKEPMDLGTILRNLKNLHYNSKKEFVHDLMLIWSNCFLYNSHPDHPLRVH 402

  Fly   570 GRKLQDVFEMRYAN-IPDEPVANAAHHHGHGHGHGHGHGHGHGHGHGHGHGHGYGGSSSLKHDAS 633
            .:.::|. .:...| |||..:.:                                     :.|..
pombe   403 AQFMKDK-SLELINLIPDIVIQS-------------------------------------RKDYD 429

  Fly   634 DSSSEDSSDTENESNSDEERSARLKMLESKLLGLQEEIRKLSEEASAKKK----AKKKLKEKKKS 694
            ||..|...:::.||.::..:....|...|:....|:.:...::..|.::.    .||:::..|..
pombe   430 DSLIEAELESDEESTAETSKHVTSKKTSSRGGQTQQAVEVHTDANSPEENNTPVTKKEVETSKPP 494

  Fly   695 IGGGS 699
            ...||
pombe   495 AVSGS 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	59/218 (27%)
		Bromo_Brdt_II_like	481..581	CDD:99930	35/109 (32%)
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
spt7	NP_596356.2	COG5076	161..554	CDD:227408	74/330 (22%)
		Bromo_SPT7_like	309..420	CDD:99942	38/116 (33%)
		Bromo_TP	707..783	CDD:284856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770