|
Fly 2 SSSEPPPRYEPPVEPVNGIVQPPVIPPAERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAK 66
:.::|.|.......| .||......:|.|.|||||||::.|:|.:|||.|:|||||||||.
Human 31 AQAQPQPANAASTNP-----PPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAV 90
Fly 67 KLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEK 131
|||||||:||||.|||||||||||||||||:|:|.||||||||.|||:|||||:|:|:||:.|||
Human 91 KLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEK 155
Fly 132 VFLQKIESMPKEELELEPVTAKGGKKKQRAPATPKSSSGGAGASTGSGTSSAAVTSGPGSGSTKV 196
:|||||..:|.||.|:..|.|||..:.::...|.| .|.||...|:.|
Human 156 LFLQKINELPTEETEIMIVQAKGRGRGRKETGTAK-----PGVSTVPNTTQA------------- 202
Fly 197 SVAASSAQQSGLQGATGAGGGSSSTPGTQPGSGAGGAIAARPVSAMGGTVSSTAGGAPSIPPIST 261
|:.|.||... |:.||:..
Human 203 ----------------------STPPQTQTPQ-------------------------PNPPPVQA 220
Fly 262 MPPHTVPG-------STNTTTTAMAGGVGGPGAAGANPNAAALMASLLNAGQTGAYPGAPGQTAV 319
.||..|. .|...|......:..|......|.. |.||....|
Human 221 -TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP----------------PPAPAPQPV 268
Fly 320 NSSSLLDGSTAAVAAAAAAAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAYVNAGVSVGVDA 384
.|.. |.:|..
Human 269 QSHP------------------------------------PIIAAT------------------- 278
Fly 385 VIPPQQPAKIKKGVKRKADTTTPTA--NAFESPYTQMDSKSAKIATRRESNRQVIGKK----GSG 443
.||.|.||||||||||||||. ...|.|....:.|:.|:..||||:|.|...| .|.
Human 279 ----PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ 339
Fly 444 YNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVD 508
.:.:| :...|:|:.||.|:.||||:|:|||:.||||||||||
Human 340 QHPAP-----------------------EKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVD 381
Fly 509 AEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKL 573
.|.||||||.||||.|||:.|:|.|::.|||:.|.||.|||||:|:||||||||||:||||.|||
Human 382 VEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKL 446
Fly 574 QDVFEMRYANIPDEP------------------VANAAHHHGHGHGHGHGHGHGHGHGHGHGHGH 620
|||||||:|.:|||| ||..:
Human 447 QDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPS--------------------------- 484
Fly 621 GYGGSSSLKHDASDSSSEDSSDTENES-NSDEERSARLKMLESKLLGLQEEIRKLSEEASAK-KK 683
:|||||:.|||:::.: :|:|||:.||..|:.:|..:.|::..||:....| ||
Human 485 -----------SSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKK 538
Fly 684 AKKKLKEKKKSIGGGSGSGSASHHCHATGGGANAGGAGGPGSGGHGSVSVPGGVGSLGPGGAGGA 748
.:|..|||||.
Human 539 KEKDKKEKKKE------------------------------------------------------ 549
Fly 749 NLNALLGGSLVGHGGAAVAGGVPNVGALHSQVHDVAMAFSQMAGGGAAAGAGFGAGVTAAGASSG 813
.|.:..:|.
Human 550 ---------------------------KHKRKEEVE----------------------------- 558
Fly 814 GKAGTLAGALAAGAAAGAGGTTAGSGSSKGAKSKGGRGAKGSGAGGVGASNNAAAGNAAGGAAGA 878
.:|.:|:|.....|.. .||::..|.
Human 559 --------------------------ENKKSKAKEPPPKKTK-------KNNSSNSNV------- 583
Fly 879 AAGAGSVGGVGGAGAAGGGNASKRAKGSSSAGAGGGVGGANASAGGAGARGSSKKKPSQVMN--- 940
|||:|:.:.:
Human 584 ----------------------------------------------------SKKEPAPMKSKPP 596
Fly 941 --FDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKP 1003
::|||||..|||||:||||||||||||||:||||||||||:|||||::|||||||||||||||
Human 597 PTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKP 661
Fly 1004 STLRELESYVASCLRKKTHKKPSGKSKDEQMAEKKQELEKRLQDVTGQLGASKKTAKKDESASSK 1068
|||||||.||.|||||| :|| .|||...: :.|||
Human 662 STLRELERYVTSCLRKK--RKP--------QAEKVDVI----------------------AGSSK 694
Fly 1069 VEAVQPANPVSSSSSSSDSSSSSSSDSSSSDSSDSEAVLV------------------------- 1108
::.. |.|.|.|||:||||||.|||..:.
Human 695 MKGF------------SSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQ 747
Fly 1109 -IPAPTGDGDERPPRKKKSRDSNGSNVNNPSINVVMGGNLPSGALSPTTMLMGLDHVVNSNTPTS 1172
.|||.......||::. |..........|.....|.:|.......:.|:.|.
Human 748 QAPAPVPQQPPPPPQQP------------PPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPP- 799
Fly 1173 QMSNMLGNANPLTAAAMLNNNNKTSLPGSNFG----------GAPAPGNMMHAGAGVPVAGAAVS 1227
.:....|:. :..||||.|. ..|.|....| :|......:
Human 800 ----FIATQVPVL---------EPQLPGSVFDPIGHFTQPILHLPQPELPPH----LPQPPEHST 847
Fly 1228 ASTGQQHNKNGPNDLSKV---QPGGPIN--AALPPHSFAGGTATVATSQSSGGIRIASNLHKPSG 1287
.....||....|..|... ||..|.| ||||| ||:
Human 848 PPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP--------------------------KPA- 885
Fly 1288 LGGGDLGEHHAALAAALTSGINSTGTAGGGINNNGGSNNNANPLGGSHGDAMVNASLASLASGLK 1352
...|::.|||. .|| :....:|
Human 886 --------RPPAVSPALTQ----------------------TPL-------LPQPPMA------- 906
Fly 1353 QIPQF----DDPVEQSLASLEFSAGSTGKSGLTDNFLMQQHLMQPAGP-------QQQ------- 1399
|.||. ::|....|.|::... :|.|...:||..| |.|
Human 907 QPPQVLLEDEEPPAPPLTSMQMQL-----------YLQQLQKVQPPTPLLPSVKVQSQPPPPLPP 960
Fly 1400 ------QQQQQQQPFGHQQQQQQQQQQQQQQQ-------QHMDYVTELLSKGAENVGGMNGNHLL 1451
|||.||||......|.|...|||.|. |.|.:.|.:
Human 961 PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHI----------------- 1008
Fly 1452 NFNLDMAAAYQQKHPQQQQQQAHNNGFNVADFGMAGFDGLNMTAASFLDLEPSLQQ----QQMQQ 1512
||..|.|.||..| .|..|| |..:.
Human 1009 ----------QQPPPPQGQQPPH---------------------------PPPGQQPPPPQPAKP 1036
Fly 1513 MQLQQQHHQQQQQQTHQQQQQHQQQ-------HHQQQQQQQLTQQQLQQQQQQQQQQQHLQQQQH 1570
.|:.|.||..:..::......|.:: |..|..|.|....|...||..|.::|.|:....
Human 1037 QQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASV 1101
Fly 1571 QQQHHQAANKLLIIPKPI-------ESMMPSPPDKQQLQQHQKVLP--PQQSPSDMK----LHPN 1622
.|.......|...|..|| .|:.|.||...:..:....|| |:..|.|:. ..|.
Human 1102 VQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPE 1166
Fly 1623 AAAAAAVASAQAKLVQTFKA-----NEQNLKNASSWSSLASANSPQSHTSSSSSSSKAKPAMDSF 1682
..|....|..:.|..|..|. .:..:||..||:||. |.|.::.||: ||.:.|||
Human 1167 QNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLV-----QKHPTTPSST--AKSSSDSF 1224
Fly 1683 QQFRNKAKERDRLKLLEAAEKEKKNQKEAAEKEQQRKHHKSSSSSLTSAAVAQAAAIAAATAAAA 1747
:|||..|:|: |..||..|.|.|.||||::|...:...|.....|:.||
Human 1225 EQFRRAAREK------EEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQA----------- 1272
Fly 1748 VTLGAAAAAALASSASNPSGGSSSGGAGSTSQQAITGDRDRDRDRERERERSGSGGGQSGNGNNS 1812
::|....|.|...::::|:..
Human 1273 -------------------------------RRAHEEARRRQEQQQQQRQEQ------------- 1293
Fly 1813 SNSANSNGPGSAGSGGSGGGGGSGPASAGGPNSGGGGTANSNSGGGGGGGGPALLNAGSNSNSGV 1877
Human 1294 ----------------------------------------------------------------- 1293
Fly 1878 GSGGAASSNSNSSVGGIVGSGGPGSNSQGSSGGGGGGPASGGGMGSGAIDYGQQVAVLTQVAANA 1942
||
Human 1294 ----------------------------------------------------QQ----------- 1295
Fly 1943 QAQHVAAAVAAQAILAASPLGAMESGRKSVHDAQPQISRVEDIKASPGGQGQSSPAQQSPQDRAA 2007
|.|..|||||| ||:| |.||| .||....
Human 1296 QQQQQAAAVAA----AATP------------------------------QAQSS----QPQSMLD 1322
Fly 2008 AKRAEQRRAEQERRRREALAGQIDMNMQSDLMAAFEETL 2046
.:|...|:.|||||||||:|..||||.||||::.|||.|
Human 1323 QQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENL 1361
| 
