DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fs(1)h and Baz1b

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_035844.2	Gene:	Baz1b / 22385	MGIID:	1353499	Length:	1479	Species:	Mus musculus

Alignment Length:	182	Identity:	46/182 - (25%)
Similarity:	75/182 - (41%)	Gaps:	48/182 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   481 LKSCNEILKELFSKKHSGYAWPFYKPV---DAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSA 542
            |:.|.:||.:|...:   ::|||.:||   :||     ||:|:|:.|||..|::.|.....|:|.
Mouse  1341 LQKCEDILHKLVKYR---FSWPFREPVTRDEAE-----DYYDVIEHPMDFQTIQNKCSCGNYRSV 1397

  Fly   543 PEFAADVRLIFTNCYKYN-PPDHDVVAMGRKLQDVFEMRYANIPDEPVANAAHHHGHGHGHGHGH 606
            .||..|::.:|.|...|| ...|.:..|.:..|.:..:...::|
Mouse  1398 QEFLTDMKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLP--------------------- 1441

  Fly   607 GHGHGHGHGHGHGHGYGGSSSLKHDASDSSSEDSSDTENESNSDEERSARLK 658
                        ||.|......|.  .|..::|..|:::|| ..:.|..|.|
Mouse  1442 ------------GHPYVRRKRRKF--PDRLADDEGDSDSES-VGQSRGRRQK 1478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	34/115 (30%)
		Bromo_Brdt_II_like	481..581	CDD:99930	33/103 (32%)
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
Baz1b	NP_035844.2	WAC_Acf1_DNA_bd	21..120	CDD:287503
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	146..212
		C motif	207..213
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	302..333
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	376..433
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	448..472
		DDT	605..669	CDD:214726
		WHIM1	725..770	CDD:292246
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	789..813
		WHIM2	900..928	CDD:292247
		WHIM3	991..1029	CDD:292248
		PHD_BAZ1B	1186..1231	CDD:277098
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1231..1324
		Bromo_WSTF_like	1340..1436	CDD:99937	33/102 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1451..1479		9/31 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900