DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fs(1)h and athp-2

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_494767.2	Gene:	athp-2 / 173769	WormBaseID:	WBGene00019217	Length:	1412	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	58/238 - (24%)
Similarity:	103/238 - (43%)	Gaps:	44/238 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 PAVAVNAANAVQ----AYVNAGVSV------GVDAVIPPQQPAKIKKGVKRKADTTTPTANAFES 414
            |.:...:..||:    :.::.|:|:      |...|.|.::|  ::....|..|.........|.
Worm  1209 PTIRTASGRAVKRVHYSDIHEGLSLKNRKSNGSMPVTPSERP--VRNVSVRIFDVENENVLTDED 1271

  Fly   415 PYTQMDSKSAKIATRRESNRQVIGKKGSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSD 479
            .....:::..|..|.::|                  |:..|     ....::.|.:...|||::
Worm  1272 DSDGENTRKRKTPTSKKS------------------VTSTP-----TTNDISRVIIPNIKEKMT- 1312

  Fly   480 ALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPE 544
               ....:|||...::.|   |||.:|||::  .:.||:|:||:||:|.|:..|:..|.|....|
Worm  1313 ---LIETLLKEAMRQECS---WPFLQPVDSK--EVPDYYDVIKRPMNLRTMMNKIKQRIYNKPIE 1369

  Fly   545 FAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDE 587
            ...|.:||.:||..||.|::::..:.|:|.|....|...|.|:
Worm  1370 VRNDFQLILSNCETYNEPENEIYKLSRELHDFMADRLDEIIDQ 1412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	51/201 (25%)
		Bromo_Brdt_II_like	481..581	CDD:99930	34/99 (34%)
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
athp-2	NP_494767.2	WAC_Acf1_DNA_bd	23..123	CDD:402251
		DDT	457..524	CDD:214726
		WHIM1	629..671	CDD:406127
		WSD	795..897	CDD:406128
		PHD	1100..1144	CDD:214584
		BROMO	1306..1409	CDD:197636	38/111 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810