DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fs(1)h and pcaf-1

DIOPT Version :9

Sequence 1:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster
Sequence 2:	NP_491173.1	Gene:	pcaf-1 / 171920	WormBaseID:	WBGene00021636	Length:	767	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	45/152 - (29%)
Similarity:	70/152 - (46%)	Gaps:	30/152 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   430 RESNRQVIGKKGSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNK----EKLSDALKS-CNEILK 489
            |||:.|:            |.:..|||...|        .:.|..    ::..|:|.| ...|||
Worm   616 RESSPQL------------LELRKVPGTDSL--------KMHKKSCYHLDERDDSLDSKIGAILK 660

  Fly   490 ELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFT 554
            :|.:.|:   ||||..|||.:  .:.:|:|.||.|:|..|::.|:..:.|.....|.||:..:|.
Worm   661 KLTADKN---AWPFASPVDVK--EVPEYYDHIKHPIDFKTMQEKLKRKAYTHQHLFIADLNRLFQ 720

  Fly   555 NCYKYNPPDHDVVAMGRKLQDV 576
            |||.:|..:......|.||.::
Worm   721 NCYVFNGAEAVYYKYGYKLNEL 742

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929
		COG5076	387..>593	CDD:227408	45/152 (30%)
		Bromo_Brdt_II_like	481..581	CDD:99930	34/97 (35%)
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
pcaf-1	NP_491173.1	PCAF_N	9..247	CDD:283997
		COG5076	408..735	CDD:227408	42/143 (29%)
		Acetyltransf_1	476..544	CDD:278980
		Bromo_gcn5_like	650..748	CDD:99941	34/98 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810