DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment fs(1)h and BAZ1A

DIOPT Version :9

Sequence 1:NP_001259321.1 Gene:fs(1)h / 31722 FlyBaseID:FBgn0004656 Length:2046 Species:Drosophila melanogaster
Sequence 2:NP_038476.2 Gene:BAZ1A / 11177 HGNCID:960 Length:1556 Species:Homo sapiens


Alignment Length:210 Identity:61/210 - (29%)
Similarity:99/210 - (47%) Gaps:38/210 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   383 DAVIPPQQPAKIKKGVKRKADTTTPTANAFESPYTQM-------DSKSAKIATR-----RESNRQ 435
            |..:....|.:.::|  ||:...|| .|:...|..::       .|:|..||::     .||.|:
Human  1346 DVFVELLSPRRKRRG--RKSANNTP-ENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRR 1407

  Fly   436 VIGKKGSGYNMSPLGVSGVPGLGGLVAGGVAGVAVAKNKEKLSDALKSCNEILKELFSKKHSGYA 500
            .  :|......||:      .||...:|...||          ..|.:..:::.||.  :|.. :
Human  1408 C--RKRQSPEPSPV------TLGRRSSGRQGGV----------HELSAFEQLVVELV--RHDD-S 1451

  Fly   501 WPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHD 565
            |||.|.|  ..:.:.||:||||||:.|..::.|::..|||.|.||..|:.|:|:||::|||.:..
Human  1452 WPFLKLV--SKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTS 1514

  Fly   566 VVAMGRKLQDVFEMR 580
            ....|.:||..|.::
Human  1515 EAKAGTRLQAFFHIQ 1529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fs(1)hNP_001259321.1 Bromo_Brdt_I_like 34..140 CDD:99929
COG5076 387..>593 CDD:227408 60/206 (29%)
Bromo_Brdt_II_like 481..581 CDD:99930 37/100 (37%)
BET 951..1015 CDD:293640
BRD4_CDT <2026..2046 CDD:293710
BAZ1ANP_038476.2 Required for interaction with NCOR1. /evidence=ECO:0000269|PubMed:17519354 1..133
Required for association with the CHRAC1/POLE3 complex 1..128
WAC_Acf1_DNA_bd 23..122 CDD:313708
DDT 422..485 CDD:214726
WHIM1 590..635 CDD:317926
Neuromodulin_N <645..788 CDD:331332
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 662..754
Interaction with SMARCA5 667..933
WSD 800..926 CDD:317927
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 841..877
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 941..966
PHD_BAZ1A 1150..1195 CDD:277097
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1202..1376 8/32 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1399..1431 9/39 (23%)
Bromo_Acf1_like 1423..1535 CDD:99936 40/122 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5076
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.900

Return to query results.
Submit another query.