Protein Alignment Tbh and Moxd1

DIOPT Version :9

• Sequence 1: NP_001284996.1
• Gene: Tbh / 31718
• FlyBaseID: FBgn0010329
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_067484.2
• Gene: Moxd1 / 59012
• MGIID: 1921582
• Length: 613
• Species: Mus musculus
• Alignment Length: 611
• Identity: 183/611 - (29%)
• Similarity: 302/611 - (49%)
• Gaps: 81/611 - (13%)

  Fly    69 PVMLL--LLMATLLTRPLSAFSNRLSDTKLHEIYLDDKEIKLSWMVDWYKQ--EVLFHLQNAFNE 129
            |:::|  ||.||....|..::.        |.:.||.:.   .:.:.|.:|  .:.|.|:...|
Mouse     5 PLLVLWALLPATAAGSPGRSYP--------HRVVLDPEG---KYWLHWGRQGERLAFRLEVRTN- 57

  Fly   130 QHRWFYLGFSKRGGLADADICFFENQNGFFNA---VTDTYTSPDGQWVRRDYQQDCEV-FKMDEF 190
              .:...|||..|.:|.|||..    .|..:.   :.|.:|:.|.: :.:|.|||..: :.|:..
Mouse    58 --GYVGFGFSPTGSMAAADIVV----GGVAHGRPYLQDYFTNADRE-LEKDAQQDYHLDYAMENS 115

  Fly   191 T---LAFRRKFDTCDPLDLRLHEGTMYVVWARGETELALEDHQFALPNVTAP--HE--AGVKMLQ 248
            |   :.|.|:..|||..|..|.:.|:.|:||....:          |..:.|  |:  .|.:.|:
Mouse   116 THTVIEFSRELHTCDVNDKSLTDSTVRVIWAYHHDD----------PGESGPKYHDLNRGTRSLR 170

  Fly   249 LLRADKILIPETELDHMEITLQEAPIPSQETTYWCHVQRLEGNLRRRHHIVQFEPLIRT--PGIV 311
            ||..:|..:..|.|.:.::..|..|||::.|||||.:.::. ..:.:||:::.||:|..  ..:|
Mouse   171 LLNPEKANVVSTVLPYFDLVNQNVPIPNKGTTYWCQMFKIP-TFQEKHHVIKVEPIIERGHENLV 234

  Fly   312 HHMEVFHCEAGEHEEIPLYNGDC--EQLPPRAKICSKVMVLWAMGAGTFTYPPEAGLPIGGPGFN 374
            ||:.|:.|.:..::.:..:..:|  ..:|.....|..|::.|.:|...|||||..||.:|.|...
Mouse   235 HHILVYQCSSNFNDSVLDFGHECYHPNMPDAFLTCETVILAWGIGGEGFTYPPHVGLSLGMPLDP 299

  Fly   375 PYVRLEVHFNNPEKQSGLVDNSGFRIKMSKTLRQYDAAVMELGLEYTDKMAIPPGQTAFPLSGYC 439
            .||.||||::||.::.||:|:||.|:..:..:|:|||.|:|.||..:....||||...|...|:|
Mouse   300 RYVLLEVHYDNPARRKGLIDSSGLRVFHTTDIRRYDAGVIEAGLWVSLFHTIPPGMPEFHSEGHC 364

  Fly   440 VADCTRAALPA---TGIIIFGSQLHTHLRGVRVLTRHFRGEQELREVNRDDYYSNHFQEMRTLHY 501
            ..:|...||.|   :||.:|...||.||.|..:..||||..:|::.:..||.|..:|||.:.|..
Mouse   365 TLECLEEALGAEKPSGIHVFAVLLHAHLAGKGIRLRHFRKGEEMKLLAYDDDYDFNFQEFQYLRE 429

  Fly   502 KPRVLPGDALVTTCYYNTKDDKTAALGGFSISDEMCVNYIHYYPATKLEVCKSSVSEETLENYFI 566
            :..:||||.|:|.|.|||||......||.|..:|||::|:.|||...|..| ||:.:...:..||
Mouse   430 EQTILPGDNLITECRYNTKDRAVMTWGGLSTRNEMCLSYLLYYPRVNLTRC-SSIPDIMEQLQFI 493

  Fly   567 YMK-------------RTEHQHGVHLNGARSSNY----RSIEWTQPRIDQLYTMYMQEPLSMQCN 614
            .:|             ::..|:       |:.::    ...:||:........:.:..|::::|:
Mouse   494 GVKEIYRPVTTWPFIIKSPKQY-------RNLSFMDAMNKFKWTKKEGLSFNKLVLSLPVNVRCS 551

  Fly   615 RSDGTRFEGRSSWEGVAATPVQIRIP 640
            ::|...:    |.:|:.|.|..|:.|
Mouse   552 KTDNAEW----SIQGMTAIPPDIKRP 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbh	NP_001284996.1	DOMON	102..220	CDD:281361	35/126 (28%)
		Cu2_monooxygen	264..389	CDD:279429	42/128 (33%)
		Cu2_monoox_C	410..565	CDD:281675	63/157 (40%)
Moxd1	NP_067484.2	DOMON_DOH	31..165	CDD:187689	39/154 (25%)
		Cu2_monooxygen	186..314	CDD:279429	42/128 (33%)
		Cu2_monoox_C	335..487	CDD:281675	63/152 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3568
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820