Protein Alignment Tbh and Moxd2

DIOPT Version :9

• Sequence 1: NP_001284996.1
• Gene: Tbh / 31718
• FlyBaseID: FBgn0010329
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_647457.2
• Gene: Moxd2 / 194357
• MGIID: 2388042
• Length: 619
• Species: Mus musculus
• Alignment Length: 608
• Identity: 172/608 - (28%)
• Similarity: 265/608 - (43%)
• Gaps: 93/608 - (15%)

  Fly    68 MPVMLLLLMATLLTRPLSAFS--NRLSDTK--LHEIYLD-DKEIKLSWMVDWYKQEVLFHLQNAF 127
            |..:||..:..||.  |:|||  .||..|.  .:..:|| .:.:.|.|..|:..:.:.|.||
Mouse     1 MACVLLFRLFLLLV--LAAFSQGKRLGPTSPLRYSRFLDPSRAVFLRWDFDYEAEIITFELQ--- 60

  Fly   128 NEQHRWFYLGFSKRGGLADADIC---FFENQNGFFNAVTDTYTSPDGQWVRRDYQQDCEVFKMDE 189
            .:...|..||.:.|.....:|:.   ...|.|.:|   :|.:.. |...:.:|..||.|:.::.|
Mouse    61 VQTTGWVGLGITDRYTFVGSDLVVGGVLPNGNVYF---SDQHLL-DEDTLEQDGSQDAELLRLTE 121

  Fly   190 ----FTLAFRRKFDTCDPLDLRLHEGTMYVVWARGETELALEDHQFALPNVTAPHE--AGVKMLQ 248
                .|:.|.|.|.||||.|..:...||.|:.|.|..:         :|.::..|.  ..:.:||
Mouse   122 DAVSTTMRFSRPFRTCDPHDRDITSDTMRVLAAYGPDD---------IPKMSREHTFVKSIFLLQ 177

  Fly   249 LLRADKILIPETELDHMEITLQEAPIPSQETTYWCHVQRLEGNLRRRHHIVQFEPLI--RTPGIV 311
            :|:.|....||..:.| ::.:....||..:|||.|....|. .:.::|||.:|||::  |...:|
Mouse   178 MLQYDDQDAPEDTIIH-DLKISNFIIPEDDTTYACTFLPLP-IVSKKHHIYKFEPILVERNETMV 240

  Fly   312 HHMEVFHCEAGEHEEIPLYNGDCEQLPPRAKICSKVMVLWAMGAGTFTYPPEAGLPIGGPGFNP- 375
            ||:.|:.|  |....:|...|:|....|...:||.|:..||:|..::.:|.:.|:.||.| |:|
Mouse   241 HHVLVYAC--GNSSVLPTGIGECYGSDPAFSLCSHVIAGWAVGGLSYQFPDDVGISIGTP-FDPQ 302

  Fly   376 YVRLEVHFNNPEKQSGLVDNSGFRIKMSKTLRQYDAAVMELGLEYTDKMAIPPGQTAFPLSGYCV 440
            ::|||:|::|.:...|:.|.||.|:..:..||:||..|::||:.......||||..||...|.|.
Mouse   303 WIRLEIHYSNFQNLPGIRDTSGMRLFYTSHLRKYDMGVLQLGISVFPIHFIPPGAEAFLSYGLCK 367

  Fly   441 ADCTRA--ALPATGIIIFGSQLHTHLRGVRVLTRHFRGEQELREVNRDDYYSNHFQEMRTLHYKP 503
            .|....  ..|.:.|.|....|||||.|..:....:|...:|:.|.:|..|..:.||.|.|.:..
Mouse   368 TDKFEELNGAPVSDIYISACLLHTHLAGRSLQALQYRNGTQLQVVCKDFSYDFNLQESRDLPHPV 432

  Fly   504 RVLPGDALVTTCYYNTKDDKTAALGGFSISDEMCVNYIHYYPATKLEVCK-------------SS 555
            .:.|||.|:..|:|.|.|......||.|..:|||:.:..|||...:..|.             ..
Mouse   433 VIKPGDELLIECHYQTLDRDFMTFGGASTINEMCLIFFFYYPRINISSCMGYPDIIYVTNELGEE 497

  Fly   556 VSEETLENYFIYMKRTEHQHGVHLNGARSSNYRSIEWTQPRIDQLYTMYMQEPLSMQCNRSDGT- 619
            .||..:||..:                    ..::|||...|         :.....|..|..|
Mouse   498 ASENPMENLMV--------------------LDNVEWTPENI---------KKAEKACKESQQTV 533

  Fly   620 -------RFEGRSSW-EGVAATP 634
                   ..|..:.| ..:..||
Mouse   534 LIKTIDEEVENTTGWIPDIIPTP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbh	NP_001284996.1	DOMON	102..220	CDD:281361	35/125 (28%)
		Cu2_monooxygen	264..389	CDD:279429	43/127 (34%)
		Cu2_monoox_C	410..565	CDD:281675	53/169 (31%)
Moxd2	NP_647457.2	DOMON_DOH	36..172	CDD:187689	39/151 (26%)
		Cu2_monooxygen	194..314	CDD:279429	42/123 (34%)
		Cu2_monoox_C	337..482	CDD:281675	48/144 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3568
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820