Protein Alignment Tbh and dbh

DIOPT Version :9

• Sequence 1: NP_001284996.1
• Gene: Tbh / 31718
• FlyBaseID: FBgn0010329
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_002942324.3
• Gene: dbh / 100492247
• XenbaseID: XB-GENE-959495
• Length: 615
• Species: Xenopus tropicalis
• Alignment Length: 601
• Identity: 238/601 - (39%)
• Similarity: 333/601 - (55%)
• Gaps: 36/601 - (5%)

  Fly    66 TFMPVMLLLLMATLLTRPLSAFSNRLSDTKLHEIYLDDK-EIKLSWMVDWYKQEVLFHLQNAFNE 129
            |.:.|.::||:|:     |...|.:...:..:::.||.: .::|.|.|.:.::.|.|.:  ...:
 Frog    23 TMLAVFMILLVAS-----LQGPSRQQKSSFPYQVPLDPQGSLQLYWNVSYSEKVVYFRI--LIKD 80

  Fly   130 QHRWFYLGFSKRGGLADADIC-FFENQNG-FFNAVTDTYTSPDGQWVRRDYQQDCEVFKMDE--- 189
            .......|.|.||...|||:. .:.|:.| ||.   |.::...|| :..|.|||.|:....:
 Frog    81 LKFGLIFGMSDRGDFEDADMAVLWTNELGSFFG---DAWSDQKGQ-LHMDSQQDYELLNAQQSQE 141

  Fly   190 -FTLAFRRKFDTCDPLDLRLHEGTMYVVWARGETELALEDHQFALPNVTAPHEAGVKMLQLLRAD 253
             ..|.|||.|.||||.|..:.:||:::::|..|...:    ..:..:|:|....|::.:|||:.|
 Frog   142 GLYLLFRRPFATCDPKDYLIEDGTVHLIYALLEKPFS----TLSSIDVSAIKNRGLQRVQLLKPD 202

  Fly   254 KILIPETELD--HMEITLQEAPIPSQETTYWCHVQRLEGNLRRRHHIVQFEPLIRTPG---IVHH 313
             :.||....|  :||:...:..||::|||||||:..|..:. .:||||.:||:| |.|   ||||
 Frog   203 -LPIPRLPADVLNMEVRAPQVLIPAKETTYWCHITELPKDF-TKHHIVMYEPVI-TKGHEAIVHH 264

  Fly   314 MEVFHCEAGEHEEIPLYNGDCE--QLPPRAKICSKVMVLWAMGAGTFTYPPEAGLPIGGPGFNPY 376
            :|||.| |..:..||.|:|.|:  ..|.....|..|:..|||||..|.||.|:||..|||..:.|
 Frog   265 IEVFQC-ASNYYTIPRYDGPCDSKMKPQSLNSCRHVLAAWAMGAKAFYYPEESGLAFGGPDSSRY 328

  Fly   377 VRLEVHFNNPEKQSGLVDNSGFRIKMSKTLRQYDAAVMELGLEYTDKMAIPPGQTAFPLSGYCVA 441
            :|||||::||.:..||.|:||.|:..:.|||:|||.:||:||.|:..|||||||..|.|:|||..
 Frog   329 LRLEVHYHNPLELKGLRDSSGIRLYYTSTLRRYDAGIMEVGLVYSPVMAIPPGQKDFLLTGYCTD 393

  Fly   442 DCTRAALPATGIIIFGSQLHTHLRGVRVLTRHFRGEQELREVNRDDYYSNHFQEMRTLHYKPRVL 506
            .||..|||:.||.||.|||||||.|..|.|...|..:|...||.|.:||.||||:|.|.....||
 Frog   394 KCTDRALPSNGIRIFASQLHTHLAGRGVSTILVREGKEAEVVNADGHYSPHFQEIRMLKKAVHVL 458

  Fly   507 PGDALVTTCYYNTKDDKTAALGGFSISDEMCVNYIHYYPATKLEVCKSSVSEETLENYFIYMKR- 570
            |||.:||:|.|||:|.|...:|||||:|||||||:||||.|.||:|||.|....|:.||..:.|
 Frog   459 PGDVMVTSCSYNTEDRKNITVGGFSITDEMCVNYVHYYPRTDLELCKSMVDPGYLQKYFHMVNRF 523

  Fly   571 TEHQHGVHLNGARSSNYRSIEWTQPRIDQLYTMYMQEPLSMQCNRSDGTRFEGRSSWEGVAATPV 635
            .........|...:..::.:.|.......|.::|...|:||.||||...||.|  .||......:
 Frog   524 NSDDVSTSPNTTVTKQFQEVPWNSFSAGVLKSLYSFAPISMHCNRSSAVRFPG--EWEKQPLPQI 586

  Fly   636 QIRIPIHRKLCPNYNP 651
            ..::|.....||..:|
 Frog   587 NEKLPSPPATCPAMDP 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbh	NP_001284996.1	DOMON	102..220	CDD:281361	38/124 (31%)
		Cu2_monooxygen	264..389	CDD:279429	60/129 (47%)
		Cu2_monoox_C	410..565	CDD:281675	88/154 (57%)
dbh	XP_002942324.3	DOMON	57..171	CDD:397434	36/119 (30%)
		Cu2_monooxygen	215..342	CDD:395859	60/129 (47%)
		Cu2_monoox_C	361..517	CDD:397669	89/155 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3339
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H615
Inparanoid	1	1.050	393	1.000	Inparanoid score	I1939
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	1	1.000	-	-		FOG0006061
OrthoInspector	1	1.000	-	-		oto105128
Panther	1	1.100	-	-	LDO	PTHR10157
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2835
SonicParanoid	1	1.000	-	-		X4984
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190