DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sn and Fscn3

DIOPT Version :9

Sequence 1:	NP_001162697.1	Gene:	sn / 31717	FlyBaseID:	FBgn0003447	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001004232.1	Gene:	Fscn3 / 296947	RGDID:	1303047	Length:	498	Species:	Rattus norvegicus

Alignment Length:	505	Identity:	132/505 - (26%)
Similarity:	220/505 - (43%)	Gaps:	43/505 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 IGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNTGE--SIIYLRSHLNKYLSVDQFGNV 89
            :|||:....|:|.|.:...:.|...||.::|.|.|..||..|  :::.|:|....||
  Rat    18 VGLISWAGTYLTFEAYKSTVTATAKSLGRRQTWELLVSNEHETQAVVRLKSLQGLYL-------- 74

  Fly    90 LCESDERDAGSRFQIS------ISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVH 148
            |||:|......:.:.|      :....:|:|.|:....|.:|......:.|.::...|...||..
  Rat    75 LCEADGTVCYGKPRTSHHGCFLLRFHRNGKWTLQCIISGRYLESDGQDVFCNSRVLSAYHMWTPR 139

  Fly   149 LAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNA 213
            .|....|.|.|.....:|....:...:.|||.:|..|:..|.|.|   :.|.|.|.|..:.:|:.
  Rat   140 PALHVHVILYSPTYHSYARADHTVGRVWVDAAVPCLEECGFLLHF---QDGCYHLETSTHHFLSR 201

  Fly   214 NGKLQVVCNEDCLFSAEYH-GGHLALRDRQGQYLSPIGSKAVLKSRSSSVTRDELFSLEDSLPQA 277
            ..:|....:....|..:.. .|.:||.|.:|..|.|.||..:|...|:.:..:|.|.|: ..|..
  Rat   202 VDRLVPKRSTQTAFHMQVRPRGLVALCDGEGGSLYPQGSHLLLGLGSTPMKGEEWFVLQ-HFPAW 265

  Fly   278 SFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATG 342
            ..:...:.|::||....:|.|..:.:.:...||.|.|..:....||:....|........|.|.|
  Rat   266 VSLKSKSRRFLSVIYDAEVCAASERLTQMSLFQYECDSESPILQLRSANGFYLAQRRHRAIIADG 330

  Fly   343 NRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESI----EEIAKFYFYLINRPILV 403
            :...:|..|.:.|: .|.::.::.||:||:...:| |..::.:|    ||:.   ....|||.||
  Rat   331 HPMESDTFFRVHWN-CGKITLQSPNGRFLSIASNG-LLMSNVTIPGPNEELG---IRFANRPFLV 390

  Fly   404 LKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRIEGESISVDADAP--- 465
            |:...|:||..:..:| |:||....:.|.:....:|:.|.:|..|.:|.|    .|.....|
  Rat   391 LRGRYGYVGSSSDHDL-LKCNMDQPDCIQLLPCHQGIYHFQAQGGSFWSI----TSFGTFRPWGK 450

  Fly   466 -SDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQ--WEF 512
             :..|.:||:..:.:.:.:..|.||.|.::|.  ||.|..:...:  |||
  Rat   451 FALNFCIELQGSSLLTVLAPNGFYLRADRSGT--LLADSEEITKECIWEF 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sn	NP_001162697.1	Fascin	33..147	CDD:283843	29/121 (24%)
		Fascin	152..270	CDD:238160	32/118 (27%)
		Fascin	275..394	CDD:238160	29/122 (24%)
		Fascin	399..512	CDD:238160	33/118 (28%)
Fscn3	NP_001004232.1	Fascin	24..138	CDD:283843	29/121 (24%)
		Fascin	263..381	CDD:238160	29/122 (24%)
		Fascin	386..498	CDD:238160	33/118 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344457
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1419861at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10551
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.040