Protein Alignment sn and Fscn2

DIOPT Version :9

• Sequence 1: NP_001162697.1
• Gene: sn / 31717
• FlyBaseID: FBgn0003447
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_006533322.1
• Gene: Fscn2 / 238021
• MGIID: 2443337
• Length: 519
• Species: Mus musculus
• Alignment Length: 518
• Identity: 192/518 - (37%)
• Similarity: 288/518 - (55%)
• Gaps: 46/518 - (8%)

  Fly    28 GLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPS-NTGESIIYLRSHLNKYLSVDQFGNVLC 91
            ||:|...:|:|||:||||:||:.||||:||:|.|||. ..|.::::..|||.:|||.::.|.|.|
Mouse    15 GLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVAC 79

  Fly    92 ESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVN 156
            |.|:.....||.:....|  |||.|::|..|.|.||..|:|.|.|.....:|.||||||..||.:
Mouse    80 EMDQPGRDCRFLVLPQPD--GRWVLQSEPHGRFFGGIEDRLSCFATAISPAELWTVHLAIHPQAH 142

  Fly   157 LRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVC 221
            |.|:.|:|:.||...:||:..|.::|||.|.|.||.|::.   ||.|.:.:::||.::|:|....
Mouse   143 LLSVSRRRYVHLCLQEDEMAADGDMPWGVDALVTLIFQSR---RYCLKSYDSRYLRSDGRLVWEP 204

  Fly   222 NEDCLFSAEYHGGHLALRDRQGQYLSPIGSKAVLKS-RSSSVTRDELFSLEDSLPQASFIAGLNL 285
            .....::.|:..|.||.:|..|:||:|:|....||: |::..::||||.||.|.||...:|. |.
Mouse   205 EAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPSKDELFDLEQSHPQVVLVAA-NR 268

  Fly   286 RYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATGNRRCADAL 350
            ||:||:||::|:|||||...:|||.::.|....:....::...||.|...||||||..:..|:.:
Mouse   269 RYISVRQGINVSANQDEELGHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTM 333

  Fly   351 FELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEIA------------------------- 390
            ||:.||| ..::.:|:||:|:..|::|.|.|.|:.:.|.:
Mouse   334 FEIEWHG-RRVALKASNGRFVCMKKNGQLAAISDFVGEHSLPSTAWKEQMGVGSGQSTSPSPAGE 397

  Fly   391 --KFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRI 453
              .|...|||||:|||:...|||.:|. |:.:|:.|::||:...:. .:.|...::...|.:|..
Mouse   398 DELFTLKLINRPLLVLRGLDGFVCHRR-GSNQLDTNRSTYDVFHLS-FRDGAYQIRGRGGGFWYT 460

  Fly   454 EGE-SISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTD---SATQWEF 512
            ... |:..|.|...| |..|.||..|:.||:..||||   :.||..||....|   ....||:
Mouse   461 GSHGSVCSDGDLAED-FLFEFRERGRLAIRALSGKYL---RGGASGLLRADADLPVGEALWEY 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sn	NP_001162697.1	Fascin	33..147	CDD:283843	50/114 (44%)
		Fascin	152..270	CDD:238160	43/118 (36%)
		Fascin	275..394	CDD:238160	46/145 (32%)
		Fascin	399..512	CDD:238160	38/116 (33%)
Fscn2	XP_006533322.1	Fascin	20..133	CDD:368822	50/114 (44%)
		Fascin	138..254	CDD:238160	43/118 (36%)
		Fascin	266..373	CDD:368822	42/108 (39%)
		Fascin	408..519	CDD:238160	38/116 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841040
Domainoid	1	1.000	115	1.000	Domainoid score	I6012
eggNOG	1	0.900	-	-		E1_2CMA3
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22722
Inparanoid	1	1.050	358	1.000	Inparanoid score	I2209
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52513
OrthoDB	1	1.010	-	-		D1419861at2759
OrthoFinder	1	1.000	-	-		FOG0002949
OrthoInspector	1	1.000	-	-		otm43095
orthoMCL	1	0.900	-	-		OOG6_104023
Panther	1	1.100	-	-	O	PTHR10551
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4757
SonicParanoid	1	1.000	-	-		X1949
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800