DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sws and BCY1

DIOPT Version :9

Sequence 1:	NP_511075.3	Gene:	sws / 31716	FlyBaseID:	FBgn0003656	Length:	1425	Species:	Drosophila melanogaster
Sequence 2:	NP_012231.1	Gene:	BCY1 / 854778	SGDID:	S000001295	Length:	416	Species:	Saccharomyces cerevisiae

Alignment Length:	385	Identity:	84/385 - (21%)
Similarity:	148/385 - (38%)	Gaps:	89/385 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   379 TRPPSSPSR-HSREEHTLSDPNPNPDGSFHGTTNLFTEVHGDAPNADLFHQQ---QQQHSVGNLS 439
            :||.|:.|: .||.......|..|.|..    :|:|.......|:....|||   :|||:....|
Yeast    70 SRPQSAQSQSRSRSSVMFKSPFVNEDPH----SNVFKSGFNLDPHEQDTHQQAQEEQQHTREKTS 130

  Fly   440 T----------RRSSI---TLM-------APD----GSHSCLQTPGVTTSIDMRLVQSSAVDSLR 480
            |          ||:|:   ||.       .||    .|...||          ||.:|...:.|.
Yeast   131 TPPLPMHFNAQRRTSVSGETLQPNNFDDWTPDHYKEKSEQQLQ----------RLEKSIRNNFLF 185

  Fly   481 KELGLSEEDSHIIEPFVELRELEPNVTLITEGNADDVCVWFVMTGTLAVYQSNQDATRAKQDKSD 545
            .:  |..:...::...:|.:.:....|:|.:|:..|. .:.|..||:..|            .:|
Yeast   186 NK--LDSDSKRLVINCLEEKSVPKGATIIKQGDQGDY-FYVVEKGTVDFY------------VND 235

  Fly   546 MLIHFVHPGEIVGGLAMLTGEASAYTIRSRSITRIAFIRRAAIYQIMRQRPRIVLDLGNGVVRRL 610
            ..::...||...|.||::.....|.|:.:.|...:..:.|....:|:         ||:...:||
Yeast   236 NKVNSSGPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKIL---------LGSSFKKRL 291

  Fly   611 --------SPLVRQCDY--------ALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITHPGG 659
                    .|:::....        |||....:.|..:.|:.:..::.|::..|.:.  ::..|
Yeast   292 MYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVD--VSKKG- 353

  Fly   660 KKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIV-VTKL 718
             :.::.:....|..|.|.::.:..|..||.|.:.:::|.|.:..|.  :|..|.| |.||
Yeast   354 -QGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQ--RLLGPAVDVLKL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sws	NP_511075.3	Crp	168..>310	CDD:223736
		CAP_ED	174..295	CDD:237999
		Crp	483..>611	CDD:223736	25/135 (19%)
		CAP_ED	484..602	CDD:237999	21/117 (18%)
		CAP_ED	620..719	CDD:237999	24/100 (24%)
		Crp	624..>727	CDD:223736	21/96 (22%)
		Pat_PNPLA6_PNPLA7	935..1240	CDD:132864
		RssA	940..1222	CDD:224666
BCY1	NP_012231.1	DD_R_PKA_fungi	7..44	CDD:213045
		CAP_ED	184..282	CDD:237999	21/112 (19%)
		CAP_ED	302..409	CDD:237999	22/112 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900