DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sws and prkg1b

DIOPT Version :9

Sequence 1:	NP_511075.3	Gene:	sws / 31716	FlyBaseID:	FBgn0003656	Length:	1425	Species:	Drosophila melanogaster
Sequence 2:	XP_009304717.2	Gene:	prkg1b / 566430	ZFINID:	ZDB-GENE-080225-40	Length:	684	Species:	Danio rerio

Alignment Length:	303	Identity:	65/303 - (21%)
Similarity:	118/303 - (38%)	Gaps:	70/303 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   421 PNADLFHQQQ--QQHSVGNLSTRRSSIT-----LMAPDGSHSCL----QTPGVTTSIDMRLVQSS 474
            |.....|:|.  |:|.    .|:|.:|:     ....|.||..|    ::|.     ...|::.:
Zfish    55 PATQQVHKQSALQEHQ----RTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQ-----SKELIKEA 110

  Fly   475 AVDS-LRKELGLSEEDSHIIEPFVELR---ELEPNVTLITEGNADDVCVWFVMTGTLAVYQSNQD 535
            .:|: ..|.|.||:     |:..|:..   |.:....:|.||:...: |:.:..|.:.|
Zfish   111 ILDNDFMKNLELSQ-----IQEIVDCMYPVEYDKESCIIKEGDVGSL-VYVMEDGKVEV------ 163

  Fly   536 ATRAKQDKSDMLIHFVHPGEIVGGLAML---TGEASAYTIRSRSI------------TRIAFIRR 585
                  .|..|.:..:.||::.|.||:|   |..|:..|:.:..:            .|...|:.
Zfish   164 ------TKEGMKLCTMGPGKVFGELAILYNCTRTATVQTLTNVKLWAIDRQCFQTIMMRTGLIKH 222

  Fly   586 AAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRM 650
            |...:.::..|.. ..|...::.:|:.::.:..|:       .|..:.||....|:.:|:..|::
Zfish   223 AEYMEFLKSVPTF-QGLQEEILSKLADVLEETHYS-------DGEYIIRQGARGDTFFIISKGKV 279

  Fly   651 RSVITH---PGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMA 690
            .  :|.   |.|....:...||||..|...:..|..||..|:|
Zfish   280 N--VTREDAPNGTPVYLRALGKGDWFGEKALQGEDIRTANVIA 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sws	NP_511075.3	Crp	168..>310	CDD:223736
		CAP_ED	174..295	CDD:237999
		Crp	483..>611	CDD:223736	28/145 (19%)
		CAP_ED	484..602	CDD:237999	26/135 (19%)
		CAP_ED	620..719	CDD:237999	19/74 (26%)
		Crp	624..>727	CDD:223736	19/70 (27%)
		Pat_PNPLA6_PNPLA7	935..1240	CDD:132864
		RssA	940..1222	CDD:224666
prkg1b	XP_009304717.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900