Protein Alignment sws and pnpla7b

DIOPT Version :10

• Sequence 1: NP_511075.3
• Gene: sws / 31716
• FlyBaseID: FBgn0003656
• Length: 1425
• Species: Drosophila melanogaster
• Sequence 2: XP_692276.6
• Gene: pnpla7b / 503936
• ZFINID: ZDB-GENE-050309-66
• Length: 1340
• Species: Danio rerio
• Alignment Length: 1373
• Identity: 605/1373 - (44%)
• Similarity: 860/1373 - (62%)
• Gaps: 121/1373 - (8%)

  Fly    26 YVSKQITATVY---MYFALVMMSLLFI-AWFLYFKRMARLRLRDEIARSISTVTNSSGDMRG--L 84
            ::..|:..|::   :..|.|.:|:|.| |.|.|.:..|                 ..|...|  .
Zfish    27 FIEDQLHTTMWTGVLIGAAVAVSILSIFALFFYRRHKA-----------------GEGQSEGPNY 74

  Fly    85 RFRKRDKMLFYGRRMLRKMKNVSGQ----MYSSGKGYKRRAVMRFARRILQLRRDNMPLEMRTVE 145
            |||||||:|||||:::||::.:|..    ..|..:..||..|:..||:||::||:  |..::..|
Zfish    75 RFRKRDKVLFYGRKIMRKVQTLSSPPTSGPVSQKRTRKRTKVLSIARKILRIRRE--PPTLQPKE 137

  Fly   146 PPAEYLEETIEGSD----RVPPDALYMLQSIRIFGHFEKPVFLRLCKHTQLLELMAGDYLFKITD 206
            ||...||..:...|    .:|.:.||||:::|:.||||||:||.||:|...::|..|:.||:..|
Zfish   138 PPPSLLEADLTEFDMQNSHLPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFVQLQQGEGLFRPGD 202

  Fly   207 PDDSVYIVQSGMINVYISNADGSTLSLKTVRKGESVTSLLSFIDVLSGNPSYYKTVTAKAIEKSV 271
            .|||:::||.|.:::.|...||:.:.:|.|..|:||.||||.:||::|.|:.||||:|:|...:.
Zfish   203 TDDSIFVVQDGRLDLCIHENDGTDVVVKHVLPGDSVHSLLSILDVITGYPAPYKTVSARAAIPTT 267

  Fly   272 VIRLPMQAFEEVFQDNPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRYKSVSTMSGP 336
            |:|||.|||:.||...|:.::||||:||:|||||.|.||.|||||..||.....:...:.:::|.
Zfish   268 VLRLPAQAFQSVFDKYPETLVRVIQIIMVRLQRVTFLALHNYLGLTTELFNPESQAVPLVSVAGV 332

  Fly   337 I-----------NSQTSQS-SRQAPNGPPMVISQMNLMQSAVSGTGSSGVSVTVTRPPSSPSRHS 389
            :           :|||::. |.:.|.......|..:.|.....|      .:..|..|::..|.|
Zfish   333 VGEAGQGRGPRRHSQTNEDVSDKVPQRSSDHYSDTSHMSREDCG------KLNCTESPTTLFRKS 391

  Fly   390 REEHTLSDPNPN-----PDGSFHGTTNLFTEVHGDAPNADLFHQQQQQHSVGNLSTRRSSITL-M 448
            |   :||.|..|     ||   |..|  |.....:||::.:..|:         |.|:.|:|: .
Zfish   392 R---SLSTPLENTHAGSPD---HNMT--FDRSSKEAPSSPIAIQK---------SNRKKSVTMHH 439

  Fly   449 APDGSHSCLQTPGVTTSI---DMRLVQSSAVDSLRKELGLSEEDSHIIEPFVELRELEPNVTLIT 510
            :|........|.|.::.|   .:..:..:|...|.|.:.|  :|.:::|..|.||:::....:.:
Zfish   440 SPSAVFHYSDTGGHSSQIHHSKVNAIFQAAKRDLLKIIQL--QDPNLLEDRVTLRQVKAGSVVAS 502

  Fly   511 EGNADDVCVWFVMTGTLAVYQSNQDATRAKQDKSDMLIHFVHPGEIVGGLAMLTGEASAYTIRSR 575
            ||: .||.|.||::|||.|||...|    ::::|.:.:  .||||:||.||:||||...:::|::
Zfish   503 EGD-QDVSVQFVISGTLHVYQRLID----REEQSCLFV--AHPGEMVGHLAVLTGEPLIFSVRAQ 560

  Fly   576 SITRIAFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSD 640
            .......|.:...|:|||..||:||::.:.||||:|..|||.|:||||:.||:|||||||.:.||
Zfish   561 RDCCFLSISKTHFYEIMRAEPRMVLNVAHTVVRRVSSFVRQIDFALDWMALEAGRAVYRQGDKSD 625

  Fly   641 STYIVLSGRMRSVITHPGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFN 705
            ||:||||||:||||....||||:.||||:|||:|:||.:|..:|.|||.|||||||||||||..|
Zfish   626 STFIVLSGRLRSVIMKDDGKKELAGEYGRGDLIGVVEALTHLNRATTVHAVRDSELAKLPEGALN 690

  Fly   706 AIKLRYPIVVTKLISFLSHRFLGSMQ-------TRS-GSGAPGAPVEANPVTHKYSTVALVPITD 762
            :||.:||.|||:||..|..:.||:||       .|| |..:|.:..:|.......|||.::|:::
Zfish   691 SIKRKYPQVVTRLIHLLGQKILGNMQQVNGPLSVRSLGFHSPTSKWDAGNPAANLSTVTILPVSE 755

  Fly   763 EVPMTPFTYELYHSLCAIGPVLRLTSDVVRKQLGSNIFEAANEYRLTSWLAQQEDRNIITLYQCD 827
            |||:|.||.||.|:|.||||.|.||||::|:.||....::.:||||:|||.||||.:.|.|||.|
Zfish   756 EVPLTAFTLELQHALSAIGPTLLLTSDIIRQHLGVAALDSVHEYRLSSWLGQQEDIHRIVLYQSD 820

  Fly   828 SSLSAWTQRCMRQADVILIVGLGDRSHLVGKFEREIDRLAMRTQKELVLLYPEASNAKPANTLSW 892
            .||:.|||||:||||.|:|||||::...||:.||.::..|:|.||:||||:.| ....||.|:.|
Zfish   821 GSLTPWTQRCIRQADCIIIVGLGEQEPTVGELERMLESSAVRAQKQLVLLHRE-DGPPPAGTVEW 884

  Fly   893 LNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGG 957
            ||.|.|:::|.|:.|..|:|:|:|..::.::|.||....|:.|||||||||.||||:|.||||||
Zfish   885 LNMRSWISRHLHLSCPHRVFSRRSLPKLREMYQRVFEKPPDRHSDFSRLARILTGNAIALVLGGG 949

  Fly   958 GARGAAHIGMLKAIQEAGIPVDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLL 1022
            ||||.:.:|:::|:.|||||||::||.|||:|:|||:..||:::.:|.:||:|:......|.::.
Zfish   950 GARGCSQVGIIRAMSEAGIPVDLIGGTSIGSLIGALYAEERSVSRMTVRARQWAMDFGSIFKKIT 1014

  Fly  1023 DLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSL 1087
            |||||:||||:|..||.:|...|.|..|||||||||.:|||||||..|:||:||||||||:||||
Zfish  1015 DLTYPVTSMFTGASFNSSIGTLFQDKQIEDLWIPYFNITTDITASSMRVHTDGSLWRYVRASMSL 1079

  Fly  1088 SGYMPPLCDPKDGHLLLDGGYVNNLPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLY 1152
            |||:||||||||||||:||||:||||||...::||..:||:||||||:||||||||.|||||||:
Zfish  1080 SGYLPPLCDPKDGHLLMDGGYINNLPADTARSMGAKLVIAVDVGSQDETDLTNYGDSLSGWWLLW 1144

  Fly  1153 KKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVG 1217
            |:.||....|||.::.:||:|||||..|||||.||:||||||:|||||:|.||.||.||||.|||
Zfish  1145 KRLNPLAEKVKVLNMAEIQTRLAYVCSVRQLELVKDSDYCEYLRPPIDRYGTLDFGKFDEIADVG 1209

  Fly  1218 YVFGKNYFESMAKAG-----RLGRFNQWFNKEPPKRVNHASLNEYTFIDLAQIVCRL-PETYAVN 1276
            :..||..|:...::|     ...:..:.|:|   .|..:|:....:|.|||:||.|: |...||.
Zfish  1210 FQHGKTVFDVWCRSGVRETIMKDQHQEEFHK---SRSTNATCPNASFTDLAEIVSRIEPVKQAVV 1271

  Fly  1277 TAELFSE-----DEDC---DGYISEPTTLNTDRRRIQVSRAGNSLSFSETEMDSDVELDLKLERK 1333
            ..|  ||     |||.   |..:|.|.:.::|.:..:...       .||...:|.:.::::.::
Zfish  1272 DEE--SEYQTDYDEDAVLSDFDLSNPNSEHSDAQEDEDEE-------EETADTADTDDEIEIRKR 1327

  Fly  1334 TDKSTQSS 1341
            ..::...|
Zfish  1328 RHRALNHS 1335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sws	NP_511075.3	CAP_ED	174..295	CDD:237999	55/120 (46%)
		Crp	484..>610	CDD:440428	46/125 (37%)
		CAP_ED	620..719	CDD:237999	67/98 (68%)
		Pat_PNPLA6_PNPLA7	935..1240	CDD:132864	192/309 (62%)
pnpla7b	XP_692276.6	None