DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sws and prkar1aa

DIOPT Version :9

Sequence 1:	NP_511075.3	Gene:	sws / 31716	FlyBaseID:	FBgn0003656	Length:	1425	Species:	Drosophila melanogaster
Sequence 2:	NP_001009989.1	Gene:	prkar1aa / 494533	ZFINID:	ZDB-GENE-050116-2	Length:	379	Species:	Danio rerio

Alignment Length:	217	Identity:	46/217 - (21%)
Similarity:	87/217 - (40%)	Gaps:	37/217 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   507 TLITEGNADDVCVWFVMTGTLAVYQSNQDATRAKQDKSDMLIHFVHPGEIVGGLAMLTGEASAYT 571
            |:|.:|:..| ..:.:..|.:.||.:|:..|.            :..|...|.||::.|...|.|
Zfish   161 TVIQQGDEGD-NFYVIDQGEMDVYVNNEWVTS------------IGEGGSFGELALIYGTPRAAT 212

  Fly   572 IRSRSITRI--------------AFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALD 622
            :|:::..::              :.:|:..:|:....:..|:..|...  .||:    ..| ||:
Zfish   213 VRAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKW--ERLT----VAD-ALE 270

  Fly   623 WIFLESGRAVYRQDESSDSTYIVLSGRMRSVITHPGGKKEI--VGEYGKGDLVGIVEMITETSRT 685
            .:..|.|:.:..|.:..|..:|:|.| ..:|:......:|.  ||.....|..|.:.::....|.
Zfish   271 TVQFEDGQKIVVQGQPGDEFFIILEG-SAAVLQRRSENEEFVEVGRLAPSDYFGEIALLMNRPRA 334

  Fly   686 TTVMAVRDSELAKLPEGLFNAI 707
            .||:|....:..||....|..:
Zfish   335 ATVVARGPLKCVKLDRPRFERV 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sws	NP_511075.3	Crp	168..>310	CDD:223736
		CAP_ED	174..295	CDD:237999
		Crp	483..>611	CDD:223736	22/117 (19%)
		CAP_ED	484..602	CDD:237999	20/108 (19%)
		CAP_ED	620..719	CDD:237999	22/90 (24%)
		Crp	624..>727	CDD:223736	20/86 (23%)
		Pat_PNPLA6_PNPLA7	935..1240	CDD:132864
		RssA	940..1222	CDD:224666
prkar1aa	NP_001009989.1	DD_RIalpha_PKA	14..62	CDD:213048
		Crp	129..>255	CDD:223736	20/106 (19%)
		CAP_ED	135..244	CDD:237999	18/95 (19%)
		Crp	247..>357	CDD:223736	27/118 (23%)
		CAP_ED	253..368	CDD:237999	27/112 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900