DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sws and prkg3

DIOPT Version :9

Sequence 1:	NP_511075.3	Gene:	sws / 31716	FlyBaseID:	FBgn0003656	Length:	1425	Species:	Drosophila melanogaster
Sequence 2:	XP_017208033.2	Gene:	prkg3 / 326020	ZFINID:	ZDB-GENE-030131-4745	Length:	745	Species:	Danio rerio

Alignment Length:	383	Identity:	81/383 - (21%)
Similarity:	144/383 - (37%)	Gaps:	93/383 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 NLMQSAVSGTGSSGVS---------VTVTRPPSSPSRHSRE----EHTLSDPNPNPDGSFHGTTN 411
            :|.|:|....||..:|         :.:.||..:..:..|:    |..||....|
Zfish    36 SLCQNAHRSGGSESLSDQCHAALVKLNLLRPMEAQLKKLRQMLEKECQLSQELKN---------- 90

  Fly   412 LFTEVHGDAPNADLFHQQQQQHSVGNL------------STRRSS----------ITLMAPDGSH 454
                     .|.||  ::|.:|...:|            :|:|:|          ..:|||:
Zfish    91 ---------QNQDL--KRQLEHKEKHLQALQERLDQLDCTTQRTSNELPKVWQGRAAVMAPE--- 141

  Fly   455 SCLQTPGVTTSIDMRLVQ--SSAVDSLRKELG-------LSEEDSHIIEPFVELRELEPNVTLIT 510
               |.|.| ..|....||  ||....:.|.:|       |.||...::...:::.:......:|.
Zfish   142 ---QVPEV-LDITANRVQKTSSETSQIVKAIGKNDFLRRLDEEQISMMVDLMKVLDCRAGDEIIK 202

  Fly   511 EGNADDVCVWFVMTGTLAVYQSNQDATRAKQDKSDMLIHFVHPGEIVGGLAMLTGEASAYTIRSR 575
            ||...| .::.|..|.|.|.|:.:|            :..:.||::.|.||:|.......::::.
Zfish   203 EGTEGD-SMYIVAAGELKVTQAGRD------------LRILSPGDMFGELAILYNCKRTASVKAI 254

  Fly   576 SITRIAFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIF-------LESGRAVY 633
            |..::..|.|.....||..:.::..:...|.::....|....|..|..|.       .:....:.
Zfish   255 SAVKLWCIERQTYRSIMTNKSKMKREQLMGFLKTARTLKALNDVQLSKIIDSMEEVRFQDNEVIV 319

  Fly   634 RQDESSDSTYIVLSGRMRSVITHPGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMAV 691
            |:....::.||:|.|.: .|.....|:::.:.:.|:|:..|.:.:|.|..||.|..||
Zfish   320 REGAEGNTFYIILKGEV-LVTKKVNGQQKTIRKMGEGEHFGELALIREILRTATCTAV 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sws	NP_511075.3	Crp	168..>310	CDD:223736
		CAP_ED	174..295	CDD:237999
		Crp	483..>611	CDD:223736	26/134 (19%)
		CAP_ED	484..602	CDD:237999	25/124 (20%)
		CAP_ED	620..719	CDD:237999	19/79 (24%)
		Crp	624..>727	CDD:223736	18/75 (24%)
		Pat_PNPLA6_PNPLA7	935..1240	CDD:132864
		RssA	940..1222	CDD:224666
prkg3	XP_017208033.2	CAP_ED	173..282	CDD:237999	24/121 (20%)
		CAP_ED	292..393	CDD:237999	21/86 (24%)
		STKc_cGK	444..699	CDD:270724
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900