back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sws and prkg2

DIOPT Version :9

Sequence 1:	NP_511075.3	Gene:	sws / 31716	FlyBaseID:	FBgn0003656	Length:	1425	Species:	Drosophila melanogaster
Sequence 2:	XP_021331649.1	Gene:	prkg2 / 100125912	ZFINID:	ZDB-GENE-060531-80	Length:	769	Species:	Danio rerio

Alignment Length:	513	Identity:	98/513 - (19%)
Similarity:	184/513 - (35%)	Gaps:	128/513 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 VIQVIMIRLQRVLFTALRNYLGLNA-ELVQNHM------RYKSVSTMSGPINSQTSQSSRQAPNG 351
            |.||:.:|::.:.....:....||| ||...|:      :.:::|.:|..:.|:
Zfish    29 VPQVLRVRVEELETHLKKKDEDLNAKELQIKHLEEQLAQQKQTLSEISDTLRSK----------- 82

  Fly   352 PPMVISQMNLMQSAVSGTGSSGVSVTVTRPPSSPSRHSREEHTLSDPNPNPDGSFHGTTNLFTEV 416
                ..|:|.:|.|:...|..|:.                      |:|..:....|.|.|..|
Zfish    83 ----CLQLNKLQDALKSQGELGLL----------------------PSPLKEKVSQGLTGLLRE- 120

  Fly   417 HGDAPNADLFHQQQQQHSVGNLSTRRSSITLMAPDGSHSCLQTPGVTTSI--DMRLVQSSAV--- 476
                                .|:.|:.:...::.:.|.....:.|:....  ..|:.:..:|
Zfish   121 --------------------TLNRRKGAKAGVSAEPSSRTYDSSGIPKFYFESARVWKEQSVKKL 165

  Fly   477 --DSLRKELGLSEEDSHIIEPFVEL---RELEPNVTLITEGNADDVCVWFVMT-GTLAVYQSNQD 535
              |:|.|...|...:...::..||.   |..:....:|.:|...:..  ||:. |.|.|||.|:
Zfish   166 LTDALNKNQYLRRLEVQQVKDMVECMYERTYQQGEYVIKQGEPGNHL--FVLADGKLDVYQHNK- 227

  Fly   536 ATRAKQDKSDMLIHFVHPGEIVGGLAMLTGEASAYTIRSRSITRIAFIRRAAIYQIMRQRPRIVL 600
                       |:..:......|.||:|.......::::.|..:...:.|...:.|||.......
Zfish   228 -----------LLTSIAVWTTFGELAILYNCTRTASVKAASNVKTWALDREVFHNIMRMTAEARH 281

  Fly   601 DLGNGVVRRLSPL----------VRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMR-SVI 654
            :.....:|.:|.|          :..|   |:..:...|..:.|:.|..::.||:.:|::: :..
Zfish   282 EQYRNFLRSVSLLASLPGDKLTKIVDC---LEVEYYNKGDYIIREGEEGNTFYIIANGKIKVTQS 343

  Fly   655 THPGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMA--------VRDSELAKLPEGLFNAIKLRY 711
            |....:.:|:...||||..|...:|::..|:..::|        |.|.|......|.|:.:| :|
Zfish   344 TQDHEEPQIINTLGKGDYFGEKALISDDVRSANIIAEEDGVECLVIDRETFSQTVGTFDELK-KY 407

  Fly   712 PIVVTKLISFLSHRFLGSMQTRSGSGAPGAPVEANPVTH--------KYSTVALVPIT 761
               :...:..|:.........||||..|    ...||:|        :.|..:.:|.|
Zfish   408 ---LQSYVDSLARDDKKRNAKRSGSCTP----PNTPVSHDMIELKERESSFASTIPFT 458

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.