DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10778 and SRT1

DIOPT Version :9

Sequence 1:	NP_001259316.1	Gene:	CG10778 / 31708	FlyBaseID:	FBgn0029980	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_013819.1	Gene:	SRT1 / 855127	SGDID:	S000004707	Length:	343	Species:	Saccharomyces cerevisiae

Alignment Length:	285	Identity:	94/285 - (32%)
Similarity:	143/285 - (50%)	Gaps:	48/285 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SWVSDYK-YTW----TERIAMRTLRACGYIPHHVAFVMDGNRRFARSQQIDKIEGHSRGFEKLAD 61
            :||.... ::|    .:.|.::.||. |.:|.||:|:||||||:|:|:::...:||..|...|..
Yeast    38 AWVMSLSLFSWFYVNLQNILIKALRV-GPVPEHVSFIMDGNRRYAKSRRLPVKKGHEAGGLTLLT 101

  Fly    62 CLRWCLDVGVREVTTFAFSIENFKRSNEEVEGLFNLAREKFARLLEETARLDE------------ 114
            .|..|..:||:.|:.:|||||||.|..|||:.|.||.          |.:|||
Yeast   102 LLYICKRLGVKCVSAYAFSIENFNRPKEEVDTLMNLF----------TVKLDEFAKRAKDYKDPL 156

  Fly   115 HGIRIRVIGNIELLPHDLQKLVASAMLSTERNDKLFLNVAFAYTSRDE----ITQAVETILRHGS 175
            :|.:||::|:..||..:::|.:......|:..|...|.:.|.||||::    |..:||..|.:.|
Yeast   157 YGSKIRIVGDQSLLSPEMRKKIKKVEEITQDGDDFTLFICFPYTSRNDMLHTIRDSVEDHLENKS 221

  Fly   176 QDLAGEDISERLLEECLYTR-HSPPPDLVFRTSGETRLSDFMMWQL-STSVLYFSNVLWPQITF- 237
                 ..|:.|.....:|.. ||...:|:.||||..||||:|:||: ..:.:.||:.|||..:|
Yeast   222 -----PRINIRKFTNKMYMGFHSNKCELLIRTSGHRRLSDYMLWQVHENATIEFSDTLWPNFSFF 281

  Fly   238 --------WHFLASILAYQRDRWQL 254
                    |.|.::|..|......|
Yeast   282 AMYLMILKWSFFSTIQKYNEKNHSL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10778	NP_001259316.1	Cis_IPPS	29..249	CDD:259850	85/246 (35%)
SRT1	NP_013819.1	uppS	68..292	CDD:129165	82/238 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0020
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1217
OMA	1	1.010	-	-		QHG60679
OrthoFinder	1	1.000	-	-		FOG0001218
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100493
Panther	1	1.100	-	-	O	PTHR10291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.660