Protein Alignment CG10778 and DHDDS

DIOPT Version :9

• Sequence 1: NP_001259316.1
• Gene: CG10778 / 31708
• FlyBaseID: FBgn0029980
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_079163.2
• Gene: DHDDS / 79947
• HGNCID: 20603
• Length: 334
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 150/330 - (45%)
• Similarity: 208/330 - (63%)
• Gaps: 34/330 - (10%)

  Fly     1 MSWVSDYKYTWTERIAMRTLRACGYIPHHVAFVMDGNRRFARSQQIDKIEGHSRGFEKLADCLRW 65
            |||:.:.:.:..||.....::| |.:|.|:||:||||||:|:..|:::.||||:||.|||:.|||
Human     1 MSWIKEGELSLWERFCANIIKA-GPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRW 64

  Fly    66 CLDVGVREVTTFAFSIENFKRSNEEVEGLFNLAREKFARLLEETARLDEHGIRIRVIGNIELLPH 130
            ||::|:.|||.:||||||||||..||:||.:|||:||:||:||..:|.:||:.|||:|::.|||.
Human    65 CLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEEKEKLQKHGVCIRVLGDLHLLPL 129

  Fly   131 DLQKLVASAMLSTERNDKLFLNVAFAYTSRDEITQAVETILRHGSQDLAG-EDISERLLEECLYT 194
            |||:|:|.|:.:|:..:|.||||.||||||.||:.||..:.....|.|.. .||||.||::||||
Human   130 DLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDKCLYT 194

  Fly   195 RHSPPPDLVFRTSGETRLSDFMMWQLSTSVLYFSNVLWPQITFWHFLASILAYQ----------- 248
            ..||.||::.|||||.|||||::||.|.|.|.|..||||:.|||:...:||.:|
Human   195 NRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHSVLQQKAR 259

  Fly   249 ------RDRWQLDDFRRA---------------ERMQSCQLAKATDFYSERVQNFLTTIDEDRRK 292
                  |.|.||:..:..               .:::..:|.|.:....||||.||..::..|..
Human   260 DMYAEERKRQQLERDQATVTEQLLREGLQASGDAQLRRTRLHKLSARREERVQGFLQALELKRAD 324

  Fly   293 LLVRL 297
            .|.||
Human   325 WLARL 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10778	NP_001259316.1	Cis_IPPS	29..249	CDD:259850	126/237 (53%)
DHDDS	NP_079163.2	Cis_IPPS	28..248	CDD:259850	125/219 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149772
Domainoid	1	1.000	256	1.000	Domainoid score	I2047
eggNOG	1	0.900	-	-		E1_COG0020
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32615
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2921
Isobase	1	0.950	-	0	Normalized mean entropy	S1217
OMA	1	1.010	-	-		QHG60679
OrthoDB	1	1.010	-	-		D1362420at2759
OrthoFinder	1	1.000	-	-		FOG0001218
OrthoInspector	1	1.000	-	-		oto89899
orthoMCL	1	0.900	-	-		OOG6_100493
Panther	1	1.100	-	-	LDO	PTHR10291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X839
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720