Protein Alignment CG10778 and NUS1

DIOPT Version :9

• Sequence 1: NP_001259316.1
• Gene: CG10778 / 31708
• FlyBaseID: FBgn0029980
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_612468.1
• Gene: NUS1 / 116150
• HGNCID: 21042
• Length: 293
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 46/234 - (19%)
• Similarity: 88/234 - (37%)
• Gaps: 48/234 - (20%)

  Fly    21 RACGYIPHHVAFVMDGNRRFARSQQIDKIEGHSRGFEKLADCLRWCLDVGVREVTTFAFSIENFK 85
            |:...:|.|:..|            |.::| ....|..:|..:.||:.||:..::.:... ..||
Human    92 RSLEKLPVHMGLV------------ITEVE-QEPSFSDIASLVVWCMAVGISYISVYDHQ-GIFK 142

  Fly    86 RSNEEVEGLFNLAREKFARLLEETARLDEHGIRIRVIGNIELLPHDLQKLVASAMLSTERNDK-- 148
            |:|              :||::|..:..:           |||..|..|.......|.:::|:
Human   143 RNN--------------SRLMDEILKQQQ-----------ELLGLDCSKYSPEFANSNDKDDQVL 182

  Fly   149 ---LFLNVAFAYTSRDEITQAVETILRHGSQ-DLAGEDISERLLEECLYTRHSPPPDLVFRTSGE 209
               |.:.|......:.:|.:|.:...:..:| .....|:....|...|.:...|.||||.:....
Human   183 NCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKFGPV 247

  Fly   210 TRLSDFMMWQLS-TSVLYFSNVLWPQITFWHFLASILAY 247
            .....|:.|.:. |.::...:.|  .|::..|.:::..|
Human   248 DSTLGFLPWHIRLTEIVSLPSHL--NISYEDFFSALRQY 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10778	NP_001259316.1	Cis_IPPS	29..249	CDD:259850	44/226 (19%)
NUS1	NP_612468.1	UppS	<120..293	CDD:223099	38/193 (20%)
		RXG motif, crucial for prenyltransferase activity. /evidence=ECO:0000269|PubMed:32817466, ECO:0000305|PubMed:28842490	290..292

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0020
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810