Protein Alignment mahe and DDX23

DIOPT Version :9

• Sequence 1: NP_001284994.1
• Gene: mahe / 31707
• FlyBaseID: FBgn0029979
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_004809.2
• Gene: DDX23 / 9416
• HGNCID: 17347
• Length: 820
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 194/538 - (36%)
• Similarity: 290/538 - (53%)
• Gaps: 86/538 - (15%)

  Fly   133 NPTYAQRYQKPNNGAGVAGGY---QSNNYNAAALGMLSKEERAEIQREKAKNPGRNL----VKPK 190
            ||.|.:|:|....|.|...|.   |.....:...|.|.::.|...::|:.:...|.|    .|.:
Human   287 NPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQR 351

  Fly   191 WENLEPFLKDFYNIHPNTLAKSEQQVAEI--------RRELEITVSGNELPHPVVSFEESSLPAH 247
            |::..               .|::::.|:        |.:..||..|.::|:|:.|:::||||.|
Human   352 WDDRH---------------WSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPH 401

  Fly   248 VIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIR----G 308
            ::|.:.:.|:.:||.||.|..||.|..||::|:|:||||||.|:::|.:|.|...|.|.|    .
Human   402 ILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESD 466

  Fly   309 EGPIALVLAPTRELAQQIQSVVRDYGHLCKP-EIRHTCIFGGSSKVPQARDLDRGVEVIIATPGR 372
            :||.|::|||||||||||:.....:|   || .||...:.||.|:..|...|..|.|::||||||
Human   467 QGPYAIILAPTRELAQQIEEETIKFG---KPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGR 528

  Fly   373 LIDFLENRNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQI-----RPD--------------- 417
            |||.||||...|.||||:||||||||:||||||.::||:|.:     :||
Human   529 LIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFE 593

  Fly   418 ------RQVVMWSATWPKEVQALAGDFLNDYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVC 476
                  ||.||::||.|..|:.||..:|.....:.|||.. ..:..:.|.|.:.:|.||.::|:.
Human   594 SGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAG-KPHERVEQKVFLMSESEKRKKLLA 657

  Fly   477 LLNE-ISPIKNSGNNGNKIIVFVETKIKVEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNG 540
            :|.: ..|         .||:||..|...:.:.:.:...||||.::||.|.|.:|:..|.:.:.|
Human   658 ILEQGFDP---------PIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAG 713

  Fly   541 KSNILIATDVASRGLDVEDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARE 605
            ..:||:|||||.||:|::|:..|:|||...:.|:|:||||||||..:.|.|.||.|.:::....|
Human   714 AKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYE 778

  Fly   606 LISVLEEAGQTPSQALLD 623
            |           .||:|:
Human   779 L-----------KQAILE 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mahe	NP_001284994.1	PTZ00110	136..656	CDD:240273	192/535 (36%)
		DEADc	239..446	CDD:238167	106/237 (45%)
		HELICc	457..594	CDD:238034	51/137 (37%)
DDX23	NP_004809.2	RS domain	1..221
		PTZ00121	<4..>351	CDD:173412	16/63 (25%)
		SF-CC1	80..>210	CDD:273721
		Q motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00552	391..419		11/27 (41%)
		DEADc_DDX23	402..628	CDD:350703	101/228 (44%)
		DEAD box. /evidence=ECO:0000255|PROSITE-ProRule:PRU00541	549..552		2/2 (100%)
		SF2_C_DEAD	639..768	CDD:350174	52/137 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D183201at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920