DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mahe and AT5G14610

DIOPT Version :9

Sequence 1:	NP_001284994.1	Gene:	mahe / 31707	FlyBaseID:	FBgn0029979	Length:	945	Species:	Drosophila melanogaster
Sequence 2:	NP_196965.2	Gene:	AT5G14610 / 831313	AraportID:	AT5G14610	Length:	712	Species:	Arabidopsis thaliana

Alignment Length:	720	Identity:	249/720 - (34%)
Similarity:	351/720 - (48%)	Gaps:	163/720 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 QQNGVAFAGNGLGGGAGGGSGGSGGYGGQRGKNPTYAQRYQKPNNGAGVAGGYQSNNYNAAALGM 165
            ||:...|.........|.||.|.....|.|             .|.||..|...||: .|:.||
plant    68 QQSSSGFNSGKEDDKYGRGSDGPKSDSGSR-------------FNEAGRTGPISSND-AASGLG- 117

  Fly   166 LSKEERAEIQREKAKNPGRNLVKPKWENLEPFLKDFYNIHPNTLAKSEQQVAEIRRELEITVSGN 230
                 .|......|:.|                       |::.|.:|.......|:.||||||.
plant   118 -----NASSGGSSARGP-----------------------PSSAAGNELSPEAYCRKHEITVSGG 154

  Fly   231 ELPHPVVSFEESSLPAHVIEE-------------------------------------------- 251
            ::|.|::|||.:.||..::.|
plant   155 QVPPPLMSFEATGLPNELLRECPNFMPYALSFVPGAIFALGGANVVRCATSLGFLQIIWSALFGG 219

  Fly   252 ------------------------MKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYM 292
                                    :...||:.|:.||:|.||||:..||:|.||:|||||||.|:
plant   220 PNFLRCPPAAGFNSYLVLPANGRMVYSAGFSAPSPIQAQSWPIAMQNRDIVAIAKTGSGKTLGYL 284

  Fly   293 LPAIVH---IGNQPPIIRGEGPIALVLAPTRELAQQIQSVVRDYGHLCKPEIRHTCIFGGSSKVP 354
            :|..:|   |.|...:    ||..|||:||||||.|||.....:|...|  |...|::||:.|.|
plant   285 IPGFMHLQRIHNDSRM----GPTILVLSPTRELATQIQVEALKFGKSSK--ISCACLYGGAPKGP 343

  Fly   355 QARDLDRGVEVIIATPGRLIDFLENRNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQ 419
            |.::::|||::::||||||.|.||.:..:|.:.:||||||||||||||||||||||:.::...||
plant   344 QLKEIERGVDIVVATPGRLNDILEMKRISLHQVSYLVLDEADRMLDMGFEPQIRKIVNEVPTKRQ 408

  Fly   420 VVMWSATWPKEVQALAGDFLNDYIQINIGSMN-LSANHNIRQIVEICTEIEKPQRLVCLLNEISP 483
            .:|::|||||||:.:|.|.|.:..|:|||::: |.||.:|.|.:|:...:||..||..:|....|
plant   409 TLMYTATWPKEVRKIAADLLVNPAQVNIGNVDELVANKSITQTIEVLAPMEKHSRLEQILRSQEP 473

  Fly   484 IKNSGNNGNKIIVFVETKIKVEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIAT 548
                   |:|||:|..||...:.:.:.: ...:.|.:|||||:|.|||.||..||:|::.:|:||
plant   474 -------GSKIIIFCSTKRMCDQLARNL-TRTFGAAAIHGDKSQAERDDVLNQFRSGRTPVLVAT 530

  Fly   549 DVASRGLDVEDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARELISVLEEA 613
            |||:|||||:|::.|:|||:||..|:||||||||||....|.|||||...:||.|.:||.:||.|
plant   531 DVAARGLDVKDIRVVVNYDFPNGVEDYVHRIGRTGRAGATGLAYTFFGDQDAKHASDLIKILEGA 595

  Fly   614 GQ-TPSQALLDLARSMPSSGGYRGNK--RW---NNNSGGDRNTGGNNGIYQQRNNNPLNYQAGNN 672
            .| .|.|     .|.|.:.||...||  ||   ::..||.|...|::| |..|..:....:..:.
plant   596 NQKVPPQ-----VREMATRGGGGMNKFRRWGTPSSGGGGGRGGYGDSG-YGGRGESGYGSRGDSG 654

  Fly   673 YNNNRSGPPTGSSYQQYAAGGNTYLQNGAGGGVNWNRMNQMGQDGGAGQQQRNGNTYRPRAPFNN 737
            |                  ||    :..:||..:|......|..|...::.|:...:|...|..:
plant   655 Y------------------GG----RGDSGGRGSWAPSRDSGSSGWGRERSRSPERFRGGPPSTS 697

  Fly   738 GGPRA 742
            ..||:
plant   698 SPPRS 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mahe	NP_001284994.1	PTZ00110	136..656	CDD:240273	224/597 (38%)
		DEADc	239..446	CDD:238167	104/277 (38%)
		HELICc	457..594	CDD:238034	63/136 (46%)
AT5G14610	NP_196965.2	WW	17..47	CDD:278809
		PTZ00110	66..623	CDD:240273	229/616 (37%)
		DUF4532	<124..190	CDD:291705	20/88 (23%)
		DEADc	231..435	CDD:238167	99/209 (47%)
		HELICc	448..576	CDD:238034	63/135 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0331
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X504
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.870