Protein Alignment mahe and ddx3xa

DIOPT Version :10

• Sequence 1: NP_572424.1
• Gene: mahe / 31707
• FlyBaseID: FBgn0029979
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_021334401.1
• Gene: ddx3xa / 566947
• ZFINID: ZDB-GENE-030131-1565
• Length: 841
• Species: Danio rerio
• Alignment Length: 751
• Identity: 245/751 - (32%)
• Similarity: 346/751 - (46%)
• Gaps: 171/751 - (22%)

  Fly    20 GYYG---NGAAAGAGGSGNGAPRHERQYYPRGNFGGAAGGAGINGAATAAGSMHFGQPYGVMTYG 81
            ||:.   ||.|..|    .|..|::|.  .||.|.|...||..|.....||       ||  ||.
Zfish   196 GYHDSRMNGTANFA----RGPLRNDRG--GRGGFRGNRNGASFNQPVHNAG-------YG--TYE 245

  Fly    82 IQNG-----------LGMGAAGSGGGNPYRQQNGVAFAGNGLGGGAGGGSGGSGGYGGQRGKNPT 135
            .::|           ...|.....|.:.:....|.:..|....||.|||:||:..:..:....
Zfish   246 NKDGGWNSVVNRDAYASFGGRSDRGKSAFFNDRGASSRGRYERGGFGGGTGGNSRWVEESRDE-- 308

  Fly   136 YAQRYQKPNNGAGVAGGYQSNNYNAAALGMLSKEERAEIQREKAKNPGRNLVKPKWENLEPFLKD 200
              :.:.||                      :...||.|.:...|.|.|.|..|
Zfish   309 --EDWSKP----------------------MPPNERLEHELFSASNTGINFEK------------ 337

  Fly   201 FYNIHPNTLAKSEQQVAEIRRELEITVSGNELPHPVVSFEESSLPAHVIEEMKRQGFTKPTAIQS 265
             |:                  ::.:..:|...|..:.||.:..:...::..:....:|:||.:|.
Zfish   338 -YD------------------DIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQK 383

  Fly   266 QGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPP------------------IIRGEGPI 312
            ...||..:.|||:..||||||||.|::||.:..|.::.|                  :.|.:.||
Zfish   384 YAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPI 448

  Fly   313 ALVLAPTRELAQQIQSVVRDYGHLCKPEIRHTCIFGGSSKVPQARDLDRGVEVIIATPGRLIDFL 377
            :||||||||||.||....|.:.:  :..:|...::||:....|.|||:||..:::||||||:|.:
Zfish   449 SLVLAPTRELALQIYDEARKFAY--RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMM 511

  Fly   378 ENRNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQ----IRPDRQVVMWSATWPKEVQALAGDF 438
            |.....|..|.||||||||||||||||||||:|:||    .:..||.:|:|||:|||:|.||.||
Zfish   512 ERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDF 576

  Fly   439 LNDYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVCLLNEISPIKNSGNNGNKIIVFVETKIK 503
            |.:||.:.:|.:. |.:.||.|.|....|.:|...|:.||       |:....:..:||||||..
Zfish   577 LEEYIFLAVGRVG-STSENITQKVVWVEENDKRSFLLDLL-------NATGKDSLTLVFVETKKG 633

  Fly   504 VEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRGLDVEDLQYVINYDY 568
            .:.:...:..|||..||||||::|.:|:..|..||:|:..|::||.||:||||:.::::|||:|.
Zfish   634 ADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDL 698

  Fly   569 PNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARELISVLEEAGQTPSQALLDLA-------- 625
            |:..|.||||||||||...||.|.:|:...|:...::|:.:|.||.|.....|.:||
Zfish   699 PSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQHKST 763

  Fly   626 -----------------RSMPSSGGYRGNKRWNNNSGGDRNTGGNNGIYQQRNNNPLNYQAGNNY 673
                             |.||..|...||:       |.|||||:.|          |...|.|.
Zfish   764 NRGRPKRFSGGFGARDYRQMPGGGNTFGNR-------GARNTGGHGG----------NRGFGGNK 811

  Fly   674 NNNRS--GPPTGSSYQQYAAGGNTYLQNGAGGGVNW 707
            ....|  |...|.:|..|  ||| |.|      |:|
Zfish   812 GGFGSFGGDSYGGTYGNY--GGN-YTQ------VDW 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mahe	NP_572424.1	DEAD-like_helicase_N	136..656	CDD:475120	195/566 (34%)
ddx3xa	XP_021334401.1	DEADc_DDX3	335..590	CDD:350809	104/288 (36%)
		SF2_C_DEAD	595..725	CDD:350174	58/136 (43%)