Protein Alignment mahe and Ddx42

DIOPT Version :10

• Sequence 1: NP_572424.1
• Gene: mahe / 31707
• FlyBaseID: FBgn0029979
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_001100529.1
• Gene: Ddx42 / 303607
• RGDID: 1304909
• Length: 929
• Species: Rattus norvegicus
• Alignment Length: 939
• Identity: 288/939 - (30%)
• Similarity: 425/939 - (45%)
• Gaps: 215/939 - (22%)

  Fly    81 GIQNGLGMG----AAGSGGGNPYRQQNGVAFAGNGLGGGAGGGSGGSG-----------GYGGQR 130
            |.:.|.|.|    :||........||:..||       ||...|.|.|           ..|.:|
  Rat     9 GTKRGFGFGGFAISAGKKEEAKLPQQSHSAF-------GAASSSSGFGKSAPPQLPSFYKIGSKR 66

  Fly   131 G---------------------------KNPTYAQRYQKP---NNGAGVAGGYQSNNYNAAALGM 165
            .                           .:||..|...||   ::.......:.:...:.||..|
  Rat    67 ANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFRSKPADSDSDDDPLEAFMAEVEDQAARDM 131

  Fly   166 LSKEE-----------RAEIQRE---------KAKNPGRNLVKPKWE-NLE-------------- 195
            ...||           |.:|:.|         .|:||...:|:.:.| |||
  Rat   132 KRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKI 196

  Fly   196 ---------------PFLKDFYNIHPNTLAKSEQQVAEIRRELEITVSGNELPHPVVSFEESSLP 245
                           ||.|:|||.|......:.||:.::|.:|.:.|||...|.|..||......
  Rat   197 IDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFD 261

  Fly   246 AHVIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIRGEG 310
            ..::.::::..:|:||.||.||.|:||||||::|||:||||||.|::.|.::||.:|..:..|:|
  Rat   262 EQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDG 326

  Fly   311 PIALVLAPTRELAQQIQSVVRDYGHLCKPEIRHTCIFGGSSKVPQARDLDRGVEVIIATPGRLID 375
            |||:::.|||||.|||.:..:.:|...  .:|...::||.|...||:.|..|.|:::.|||||||
  Rat   327 PIAVIVCPTRELCQQIHAECKRFGKAY--NLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLID 389

  Fly   376 FLENRNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQVVMWSATWPKEVQALAGDFLN 440
            .::.:.|||||.:|||.||||||.|||||.|:|.|...:|||||.:::|||:.|:::.||.|.|.
  Rat   390 HVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILI 454

  Fly   441 DYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVCLLNEISPIKNSGNNGNKIIVFVETKIKVE 505
            |.|::..|.:. .||.::.|||||..  ..|.:...|...:....:||:    :::||..|...|
  Rat   455 DPIRVVQGDIG-EANEDVTQIVEILH--SGPSKWNWLTRRLVEFTSSGS----VLLFVTKKANAE 512

  Fly   506 DILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRGLDVEDLQYVINYDYPN 570
            ::...::.||:|...:|||..|:||:.|:.||:.....:|:|||||:||||:..::.|||||...
  Rat   513 ELANNLKQEGHNLGLLHGDMDQSERNKVILDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVAR 577

  Fly   571 SSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARELISVLEEAGQTPSQALLDLARSMPSSGGYR 635
            ..:.:.||||||||..:.|.|||..||.::..|.:|:..||.|.|..|:.|||||.   .:..:|
  Rat   578 DIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAM---QNAWFR 639

  Fly   636 GNKRWNNNSGGDRNTGGNNGIYQQR------------NNNPL-NYQAGNNYNNNRSGPPTG---- 683
             ..|:....|...|.||....|::|            |||.: ||:|   |.     |.||
  Rat   640 -KSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSNYEA---YK-----PSTGAMGD 695

  Fly   684 ----------SSYQQY---------AAGGNTYLQNGAGGGVNWNRMNQMGQDGGAGQQQRNGNTY 729
                      |.|:.:         .||.:|   .||.|..:...:|.:..:  :.||..|.
  Rat   696 RLTAMKAAFQSQYKSHFVAASLSNQKAGTST---AGASGWTSAGSLNSVPTN--SAQQGHNS--- 752

  Fly   730 RPRAP----------FNNGG---------PRAIMGHQGGGVGAGGA---AGVGG--GPQQLMAPQ 770
             |..|          |||.|         |.  :|.||....|.|:   .|:||  |.::.....
  Rat   753 -PDNPITSSTKNIPGFNNSGNISSAPVTYPS--IGAQGVNNTASGSNSREGIGGGNGKRERYTEN 814

  Fly   771 QGGQYMPQAYRGRSQFVPQG--AGAGGMPPRFQQYPK-----REYQQQGVTHYGQQALQHQQQQ- 827
            :||        ||......|  .|.||......:||:     .:..:.|.|.:|..|.:|.:.:
  Rat   815 RGG--------GRHSHGDSGNRHGDGGRHGDGYRYPESSSRHTDGHRHGETRHGGSASRHGESRG 871

  Fly   828 ---QQAGQQTKPPKDESNKYVPSAAVTSS 853
               .:.|:..|...:..|:..|.  |.||
  Rat   872 ANDGRNGESRKEGFNRENRMDPK--VDSS 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mahe	NP_572424.1	DEAD-like_helicase_N	136..656	CDD:475120	207/572 (36%)
Ddx42	NP_001100529.1	SrmB	254..677	CDD:440279	174/435 (40%)
		dermokine	<644..>889	CDD:455732	61/271 (23%)