DRSC/TRiP Functional Genomics Resources

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Protein Alignment mahe and Ddx23

DIOPT Version :9

Sequence 1:NP_001284994.1 Gene:mahe / 31707 FlyBaseID:FBgn0029979 Length:945 Species:Drosophila melanogaster
Sequence 2:NP_001100263.2 Gene:Ddx23 / 300208 RGDID:1308685 Length:819 Species:Rattus norvegicus


Alignment Length:538 Identity:194/538 - (36%)
Similarity:290/538 - (53%) Gaps:86/538 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   133 NPTYAQRYQKPNNGAGVAGGY---QSNNYNAAALGMLSKEERAEIQREKAKNPGRNL----VKPK 190
            ||.|.:|:|....|.|...|.   |.....:...|.|.::.|...::|:.:...|.|    .|.:
  Rat   286 NPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQR 350

  Fly   191 WENLEPFLKDFYNIHPNTLAKSEQQVAEI--------RRELEITVSGNELPHPVVSFEESSLPAH 247
            |::..               .|::::.|:        |.:..||..|.::|:|:.|:::||||.|
  Rat   351 WDDRH---------------WSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPH 400

  Fly   248 VIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIR----G 308
            ::|.:.:.|:.:||.||.|..||.|..||::|:|:||||||.|:::|.:|.|...|.|.|    .
  Rat   401 ILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESD 465

  Fly   309 EGPIALVLAPTRELAQQIQSVVRDYGHLCKP-EIRHTCIFGGSSKVPQARDLDRGVEVIIATPGR 372
            :||.|::|||||||||||:.....:|   || .||...:.||.|:..|...|..|.|::||||||
  Rat   466 QGPYAIILAPTRELAQQIEEETIKFG---KPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGR 527

  Fly   373 LIDFLENRNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQI-----RPD--------------- 417
            |||.||||...|.||||:||||||||:||||||.::||:|.:     :||               
  Rat   528 LIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFE 592

  Fly   418 ------RQVVMWSATWPKEVQALAGDFLNDYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVC 476
                  ||.||::||.|..|:.||..:|.....:.|||.. ..:..:.|.|.:.:|.||.::|:.
  Rat   593 SGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAG-KPHERVEQKVFLMSESEKRKKLLA 656

  Fly   477 LLNE-ISPIKNSGNNGNKIIVFVETKIKVEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNG 540
            :|.: ..|         .||:||..|...:.:.:.:...||||.::||.|.|.:|:..|.:.:.|
  Rat   657 ILEQGFDP---------PIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAG 712

  Fly   541 KSNILIATDVASRGLDVEDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARE 605
            ..:||:|||||.||:|::|:..|:|||...:.|:|:||||||||..:.|.|.||.|.:::....|
  Rat   713 AKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYE 777

  Fly   606 LISVLEEAGQTPSQALLD 623
            |           .||:|:
  Rat   778 L-----------KQAILE 784

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maheNP_001284994.1 PTZ00110 136..656 CDD:240273 192/535 (36%)
DEADc 239..446 CDD:238167 106/237 (45%)
HELICc 457..594 CDD:238034 51/137 (37%)
Ddx23NP_001100263.2 SF-CC1 79..>207 CDD:273721
DEADc_DDX23 401..627 CDD:350703 101/228 (44%)
SF2_C_DEAD 638..767 CDD:350174 52/137 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D183201at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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